ACICLOVIR-5%W/WOther disorders of kidney and ureter, not elsewhere classified
How does the disease interact with Acylovir Cream 10 gm:
Acyclovir should be used with caution to patients who have impaired kidney function. In patients with moderate to severe renal impairment, dosage modifications are advised.
How to manage the interaction:
The use of Acylovir Cream 10 gm in kidney disease patients is not advised as it may increase the severity of kidney disease. Your doctor may adjust the dosing according to the severity of your kidney disease.
ACICLOVIR-5%W/WVolume depletion
How does the disease interact with Acylovir Cream 10 gm:
Patients who are dehydrated may be more susceptible to nephrotoxicity from using acyclovir. Acyclovir should be infused intravenously over the course of an hour, along with appropriate hydration.
How to manage the interaction:
Acylovir Cream 10 gm is excreted through the kidneys, dehydration may cause damage to kidney functions. Acylovir Cream 10 gm infusion over an hour is recommended in dehydrated patients. Urine output should be monitored.
ACICLOVIR-5%W/WCare involving dialysis
How does the disease interact with Acylovir Cream 10 gm:
Hemodialysis effectively removes acyclovir from the body. Following 6 hours of dialysis, it has been demonstrated that plasma levels of acyclovir decrease by 60%. After hemodialysis, acyclovir should be administered. If not, a second dosage might be administered following each hemodialysis session.
How to manage the interaction:
Patients undergoing hemodialysis should be given Acylovir Cream 10 gm after completing hemodialysis as hemodialysis removes 60% of Acylovir Cream 10 gm from the body.