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  1. Home
  2. Medicine

  3. Oflokem-D Drops 10Ml

Prescription drug
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Oflokem-D Drops 10Ml
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Written By Divya L , PharmaD
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD

Composition :

DEXAMETHASONE-0.1%W/V+OFLOXACIN-0.3%W/V

Manufacturer/Marketer :

Alkem Laboratories Ltd

Consume Type :

Eye/Ear

Expires on or after :

Return Policy :

Not Returnable

Therapeutic Class

[ANTIBIOTICS AND CORTICOSTEROIDS]

Country of origin

India

Manufacturer/Marketer address

Alkem Laboratories Limited, Devashish Building, Alkem House, Senapati Bapat Road, Lower Parel, Mumbai - 400 013.
Other Info - OFL0418

Author Details

Doctor image

Written By

Divya L

PharmaD

Dr Aneela SiddabathuniDoctor badge

Reviewed By

Dr Aneela Siddabathuni

MPharma., PhD

Last Updated

Jul 8, 2025 | 9:47 AM IST

Doctor imageWe provide you with authentic, trustworthy and relevant information

FAQs

Oflokem-D Drops contains Ofloxacin and Dexamethasone. It helps treat bacterial infections of the eye and ear by preventing bacteria growth and reduces the redness and itchiness in the infected areas.

It is advised to remove your contact lens if you are wearing it while administering eye drops. Also, remember to wash your hands before and after administering eye drops to avoid contamination.

If you use other eye ointments/drops along with Oflokem-D Drops, it is advised to maintain a gap of at least 5-10 minutes after each administration. Also, use eye drops before applying any ointments.

Apply the drops as soon as possible. However, if it is time for the next dose, skip the missed dose and return to your regular dosing schedule.

Disclaimer

While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.
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Alcohol

Safe if prescribed

It is not known whether alcohol interacts with Oflokem-D Drops. Hence, it is advised to limit alcohol consumption while you are being treated with Oflokem-D Drops.

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Pregnancy

Consult your doctor

Limited information is available on the use of Oflokem-D Drops in pregnancy. If you are pregnant, please consult your doctor before using Oflokem-D Drops.

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Breast Feeding

Consult your doctor

If you are breastfeeding, please consult your doctor before using Oflokem-D Drops.

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Driving

Safe if prescribed

Oflokem-D Drops may cause side effects like blurred vision or dizziness, affecting your driving ability. Do not drive or operate machinery in such cases. Drive only when you are alert and have clear vision.

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Liver

Consult your doctor

Let your doctor know if you have any history of liver diseases before taking Oflokem-D Drops.

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Kidney

Consult your doctor

Let your doctor know if you have any history of kidney diseases before taking Oflokem-D Drops.

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Children

Safe if prescribed

Please consult your doctor. Your doctor will prescribe this medicine based on the condition of your child.

Product Substitutes

Reference

  1. https://zuchepharma.com/pharmaceuticals/ofloxacin-and-dexamethasone-sodium-phosphate-eye-and-ear-drops/
  2. https://www.webmd.com/drugs/2/drug-75004/dexamethasone-ophthalmic-eye/details
  3. https://www.webmd.com/drugs/2/drug-5488/ofloxacin-otic-ear/details#
  4. https://www.webmd.com/drugs/2/drug-75044/ofloxacin-ophthalmic-eye/details

About Oflokem-D Drops

Oflokem-D Drops is a combination of corticosteroid and an antibiotic that treats bacterial infections of the eye and ear. Bacterial infection occurs when bacteria invade and multiply in the body. 

Oflokem-D Drops contains Dexamethasone and Ofloxacin. Dexamethasone belongs to the class of corticosteroids. It blocks the production of prostaglandins (chemical messengers) that make the affected area red, swollen, and itchy. Ofloxacin belongs to a class of drugs called quinolone antibiotics. It is bactericidal (kills bacteria) and works by inhibiting bacterial DNA gyrase, an enzyme required for the replication, transcription, and repair of the DNA. 

Your doctor will advise the appropriate dose that suits your infection. Oflokem-D Drops is for external use only. Common side effects of Oflokem-D Drops when used as eye drops include irritation, itching, redness, burning or a stinging sensation, and temporary blurred vision. The side effects of ear drops include mild irritation, ear discomfort, headache, earache, taste changes, and dizziness. Most of these side effects do not require medical attention and gradually resolve over time. If these side effects persist longer, please consult your doctor.

Let your doctor know if you are sensitive to Oflokem-D Drops or any other medications. Please inform your doctor if you have frequent ear infections, perforated ear drum, recent eye surgery, cataracts, glaucoma, severe nearsightedness, or diabetes before using Oflokem-D Drops. Pregnant and breastfeeding mothers should consult the doctor before starting Oflokem-D Drops. This medicine may cause temporary blurred vision; hence drive only when alert. Oflokem-D Drops should be used for children only when advised by a doctor.

Uses of Oflokem-D Drops

Bacterial infections of the eye and ear.

Medicinal Benefits Mweb

Key Benefits

Oflokem-D Drops contains Dexamethasone and Ofloxacin. Dexamethasone is a corticosteroid and blocks prostaglandins' production (chemical messengers) that make the affected area red, swollen and itchy. Ofloxacin is a quinolone antibiotic that inhibits bacterial DNA gyrase, an enzyme required for DNA replication, transcription, and repair. Thus Oflokem-D Drops treats bacterial eye and ear infections.

Directions for Use

Eye drops: Tilt your head back and pull your lower eyelid downwards and outwards. Gently squeeze the dropper and put the eye drops inside the eye/eyes. Blink a few times to spread the medication inside your eye. Ear drops: Do not touch the dropper; hold it close to the ear by tilting your head to the side. Gently squeeze the dropper and put the ear drops inside the ear. Keep your head tilted for a minute to let the drops soak in.

Side Effects of Oflokem-D Drops

Eye drops:

  • Irritation
  • Itching
  • Redness
  • Burning or a stinging sensation
  • Temporary blurred vision

Ear drops:

  • Mild irritation
  • Ear discomfort
  • Headache
  • Earache
  • Taste changes
  • Dizziness 

Drug Warnings

Before using Oflokem-D Drops, let your doctor know if you have a history of eye problems (glaucoma and cataract), heart, liver or kidney diseases, frequent ear infections, perforated ear drum, recent eye surgery, severe nearsightedness, and diabetes. Avoid touching the dropper with bare hands while administering drops since it contaminates the dropper tip and solution. It is advised to check with your doctor before using Oflokem-D Drops if you are pregnant or breastfeeding. Avoid driving or operating machines since the administration of eye drops may cause blurred vision for a while after use. Oflokem-D Drops should be used for children only when advised by a doctor.

Drug-Drug Interactions

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OfloxacinAmiodarone
Critical
OfloxacinZiprasidone
Critical

Drug-Drug Interactions

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OfloxacinAmiodarone
Critical
How does the drug interact with Oflokem-D Drops 10 ml:
The combination of Amiodarone and Oflokem-D Drops 10 ml may significantly increase the risk of an abnormal heart rhythm.

How to manage the interaction:
Although Amiodarone and Oflokem-D Drops 10 ml interact, it can be taken if prescribed by a doctor. If you get dizziness, lightheadedness, fainting, or fast or racing heartbeats, consult a doctor. Do not stop taking any medications without consulting a doctor.
OfloxacinZiprasidone
Critical
How does the drug interact with Oflokem-D Drops 10 ml:
Coadministration of Oflokem-D Drops 10 ml with Ziprasidone can increase the risk or severity of irregular heart rhythm.

How to manage the interaction:
Taking Oflokem-D Drops 10 ml with Ziprasidone together can result in an interaction, it can be taken if your doctor has advised it. However, if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, chest pain or tightness, rapid heartbeat, or memory loss, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
OfloxacinSaquinavir
Critical
How does the drug interact with Oflokem-D Drops 10 ml:
Coadministration of Oflokem-D Drops 10 ml with Saquinavir can increase the risk or severity of irregular heart rhythms.

How to manage the interaction:
Taking Oflokem-D Drops 10 ml with Saquinavir together is generally avoided as it can result in an interaction, it can be taken if your doctor has advised it. However, if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, chest pain or tightness, rapid heartbeat, or memory loss, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
OfloxacinCisapride
Critical
How does the drug interact with Oflokem-D Drops 10 ml:
Coadministration of Oflokem-D Drops 10 ml with Cisapride can increase the risk or severity of irregular heart rhythms.

How to manage the interaction:
Taking Oflokem-D Drops 10 ml with Cisapride together can result in an interaction, it can be taken if your doctor has advised it. However, if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, chest pain or tightness, rapid heartbeat, or memory loss, contact a doctor immediately. Do not discontinue any medications without consulting a doctor. Note: Cisapride is no longer available on the market. Cisapride should only be taken if prescribed by a doctor and closely monitored.
OfloxacinPimozide
Critical
How does the drug interact with Oflokem-D Drops 10 ml:
Coadministration of Oflokem-D Drops 10 ml with Pimozide can increase the risk or severity of irregular heart rhythms.

How to manage the interaction:
Taking Oflokem-D Drops 10 ml with Pimozide together can result in an interaction, it can be taken if your doctor has advised it. However, if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, chest pain or tightness, rapid heartbeat, or memory loss, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
OfloxacinDronedarone
Critical
How does the drug interact with Oflokem-D Drops 10 ml:
Coadministration of Oflokem-D Drops 10 ml with Dronedarone can increase the risk or severity of irregular heart rhythm.

How to manage the interaction:
Taking Oflokem-D Drops 10 ml with Dronedarone together can result in an interaction, it can be taken if your doctor has advised it. However, if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, chest pain or tightness, rapid heartbeat, or memory loss, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
OfloxacinDisopyramide
Critical
How does the drug interact with Oflokem-D Drops 10 ml:
Coadministration of Oflokem-D Drops 10 ml with Disopyramide can increase the risk of irregular heart rhythms.

How to manage the interaction:
Taking Oflokem-D Drops 10 ml with Disopyramide together is not recommended as it can result in an interaction, it can be taken if your doctor has advised it. However, if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, or rapid heartbeat, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
OfloxacinBepridil
Critical
How does the drug interact with Oflokem-D Drops 10 ml:
Using bepridil together with Oflokem-D Drops 10 ml drugs can increase the risk of an irregular heart rhythm that may be serious.

How to manage the interaction:
Taking Oflokem-D Drops 10 ml with Bepridil can cause an interaction, please consult your doctor before taking it. You should seek immediate medical attention if you develop sudden dizziness, lightheadedness, fainting, or fast or pounding heartbeats. Do not stop using any medications without consulting a doctor.
OfloxacinSotalol
Critical
How does the drug interact with Oflokem-D Drops 10 ml:
Coadministration of Oflokem-D Drops 10 ml with Sotalol can increase the risk or severity of irregular heart rhythms.

How to manage the interaction:
Taking Oflokem-D Drops 10 ml with Sotalol together is generally avoided as it can result in an interaction, it can be taken if a doctor has advised it. If you experience sudden dizziness, lightheadedness, fainting, shortness of breath, chest pain or tightness, rapid heartbeat, or memory loss, contact a doctor. Do not discontinue any medications without consulting a doctor.
OfloxacinQuinidine
Critical
How does the drug interact with Oflokem-D Drops 10 ml:
Coadministration of Oflokem-D Drops 10 ml with Quinidine can increase the risk or severity of irregular heart rhythms.

How to manage the interaction:
Taking Oflokem-D Drops 10 ml with Quinidine together is generally avoided as it can result in an interaction, it can be taken if your doctor has advised it. However, if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, chest pain or tightness, rapid heartbeat, or memory loss, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Drug-Diseases Interactions

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No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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Habit Forming

No

Special Advise

It is advised to contact your doctor if the infection symptoms persist or worsen after two weeks of treatment.

Diet & Lifestyle Advise

  • Manage stress, eat healthily, drink plenty of water, exercise regularly, and get plenty of sleep.
  • Eat food rich in antioxidants such as berries, spinach, kidney beans, dark chocolate, etc.
  • Know your allergy triggers, such as pollen, dust and other factors.
  • Avoid getting things like shampoo, soap, and water into the ear, as it can cause itching.
  • Do not poke or scratch the ear, as it can cause damage to the ear canal, leading to inflammation. The inflamed skin can be infected by bacteria or fungi, which can cause infections in the ear.
  • Do not rub your eyes even though some ophthalmic drugs make your eye itchy.
  • If you wear contact lenses: Clean and replace contact lenses more often. Never share contact lenses. Always remember to wash your hands before inserting and after removing the contact lens. 
  • Avoid staring at digital screens for longer durations. Rest your eyes every 20 minutes.
  • Avoid or limit the intake of alcohol and caffeine.

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