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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Hari Kumar , MBBS
48 Hrs returnable
COD available

Online payment accepted

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Whats That

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Composition :

PIRFENIDONE-200MG

Manufacturer/Marketer :

Cipla Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

Therapeutic Class

MISCELLANEOUS

Country of origin

India

Manufacturer/Marketer address

Cipla House, Peninsula Business Park, Ganpatrao Kadam Marg, Lower Parel, Mumbai-400013
Other Info - PIR0134

Author Details

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FAQs

Pirfenex 200 mg Table helps in reducing the scarring and swelling in the lungs by decreasing the release/activity of naturally occurring growth factors in the body, thereby helps you breathe better.

Pirfenex 200 mg Table might make you photosensitive (sensitivity to sunlight). Avoid exposure to sunlight and sunlamps. Wear SPF 50+ sunscreen and protective clothing to reduce exposure to sunlight. Talk to your doctor if you are taking any medicines known to cause photosensitivity. If you notice any symptoms of photosensitivity, consult a doctor.

Do not discontinue Pirfenex 200 mg Table without consulting your doctor. To treat your condition effectually, continue taking Pirfenex 200 mg Table for as long as prescribed. Do not be reluctant to speak with your doctor if you experience any difficulty while taking Pirfenex 200 mg Table .

Diarrhoea might be a side-effect of Pirfenex 200 mg Table . Drink lots of fluids and eat non-spicy food if you experience diarrhoea. If you find blood in stools (tarry stools) or if you have severe diarrhoea, consult your doctor. Do not take anti-diarrheal medicine on your own.

No, avoid smoking prior to the start of the treatment and while taking Pirfenex 200 mg Table as smoking might alter the effectiveness of Pirfenex 200 mg Table .

Weight loss could occur due to loss of appetite. Maintain proper weight by eating healthy food. Your doctor might monitor your weight whilst taking Pirfenex 200 mg Table . Consult your doctor if you notice severe weight loss.

Disclaimer

While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.
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Alcohol

Caution

It is not known if alcohol interacts with Pirfenex 200 mg Table . However, avoid consumption of alcohol while taking Pirfenex 200 mg Table as it may cause increased dizziness.

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Pregnancy

Caution

Please consult your doctor if you have any concerns regarding this; your doctor will prescribe only if the benefits outweigh the risks.

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Breast Feeding

Caution

Consult your doctor if you are breastfeeding; your doctor will decide whether Pirfenex 200 mg Table can be taken by breastfeeding mothers or not.

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Driving

Caution

Pirfenex 200 mg Table might cause dizziness and tiredness. Drive or operate machinery only if you are alert.

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Liver

Caution

Dose adjustment may be needed. Please consult your doctor if you have a liver impairment or any concerns regarding this. Pirfenex 200 mg Table is not recommended for patients with severe hepatic impairment.

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Kidney

Caution

Dose adjustment may be needed. Please consult your doctor if you have kidney impairment or any concerns. Pirfenex 200 mg Table is not recommended for patients with an end-stage renal disease requiring dialysis.

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Children

Unsafe

Pirfenex 200 mg Table is not recommended for children below 18years as the safety and effectiveness has not been established.

About Pirfenex 200 mg Table

Pirfenex 200 mg Table is an anti-fibrotic medicine used to treat idiopathic pulmonary fibrosis (IPF) in adults. IPF is an irreversible disease that is marked by a progressive decline in lung function. The tissues in the lungs become swollen and scarred over time, due to which it gets difficult to breathe deeply. The scarring makes it hard for the lungs to work properly.
 
Pirfenex 200 mg Table contains ‘Pirfenidone’, which helps in reducing the scarring and swelling in the lungs by decreasing the release/activity of naturally occurring growth factors in the body, thereby helps you breathe better. Pirfenex 200 mg Table helps in slowing down the progress of idiopathic pulmonary fibrosis. 

In some cases, you may experience certain common side effects such as nausea, tiredness, diarrhoea, indigestion, loss of appetite, headache, and photosensitivity. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side effects persistently.
 
Consult your doctor before taking Pirfenex 200 mg Table if you are pregnant or breastfeeding. Pirfenex 200 mg Table may cause tiredness and dizziness, so drive with caution. Avoid consuming alcohol with Pirfenex 200 mg Table as it could lead to increased dizziness. Pirfenex 200 mg Table is not recommended for children below 18 years as safety and effectiveness have not been established. Keep your doctor informed about your health condition and medicines to rule out any side effects.

Uses of Pirfenex 200 mg Table

Idiopathic pulmonary fibrosis

Medicinal Benefits Mweb

Medicinal Benefits

Pirfenex 200 mg Table is an anti-fibrotic medicine used to treat idiopathic pulmonary fibrosis (IPF) in adults. Pirfenex 200 mg Table can help effectively slow the rate of lung function decline by 50%. Pirfenex 200 mg Table helps reduce the scarring and swelling in the lungs by decreasing the release/activity of naturally occurring growth factors in the body, thereby helps you breathe better. Pirfenex 200 mg Table helps in slowing down the progress of idiopathic pulmonary fibrosis.

Directions for Use

Take Pirfenex 200 mg Table with food. Swallow Pirfenex 200 mg Table as a whole with a glass of water; do not chew or crush it.

Side Effects of Pirfenex 200 mg Table

  • Nausea
  • Tiredness
  • Diarrhoea
  • Indigestion/Stomach upset
  • Loss of appetite
  • Headache
  • Photosensitivity

Drug Warnings

Do not take Pirfenex 200 mg Table if you are allergic to any of its components; if you have a severe or end-stage liver impairment or kidney disease requiring dialysis; if you are taking fluvoxamine (anti-depressant). Inform your doctor if you are taking any medicines that might make you photosensitive, if you smoke or have kidney or liver problems. Consult your doctor before taking Pirfenex 200 mg Table if you are pregnant or breastfeeding. Pirfenex 200 mg Table may cause tiredness and dizziness, so drive with caution. Avoid consuming alcohol with Pirfenex 200 mg Table as it could lead to increased dizziness. Pirfenex 200 mg Table is not recommended for children below 18 years as safety and effectiveness have not been established.

Drug-Drug Interactions

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Drug-Drug Interactions

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How does the drug interact with Pirfenex 200 mg Table:
Taking Pirfenex 200 mg Table with rifampicin can reduce the levels and effects of Pirfenex 200 mg Table

How to manage the interaction:
Although there is an interaction between Pirfenex 200 mg Table and rifampicin, they can be taken together if prescribed by a doctor. However, if you experience any unusual symptoms, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Pirfenex 200 mg Table:
When Pirfenex 200 mg Table is taken with Phenobarbital, it can decrease the effects of Pirfenex 200 mg Table.

How to manage the interaction:
Taking Pirfenex 200 mg Table with Phenobarbital is not recommended but can be taken if prescribed by the doctor. Do not discontinue any medication without consulting a doctor.
How does the drug interact with Pirfenex 200 mg Table:
Coadministration of Pirfenex 200 mg Table with primidone can reduce levels and the effects of Pirfenex 200 mg Table.

How to manage the interaction:
Although there is an interaction between Pirfenex 200 mg Table and primidone, they can be taken together if advised by your doctor. However, if you experience any unusual symptoms, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Pirfenex 200 mg Table:
Taking Pirfenex 200 mg Table with Carbamazepine it reduces the levels and effects of Pirfenex 200 mg Table.

How to manage the interaction:
Taking Pirfenex 200 mg Table with Carbamazepine is not recommended but can be taken if prescribed by the doctor. However, if you experience any unusual symptoms contact a doctor immediately. Do not stop using any medications without talking to a doctor.
How does the drug interact with Pirfenex 200 mg Table:
Taking Teriflunomide with Pirfenex 200 mg Table may increase the risk of liver damage.

How to manage the interaction:
Although taking Pirfenex 200 mg Table and Teriflunomide together can cause an interaction, it can be taken if your doctor has suggested it. However, if you have any of the following symptoms: fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, fatigue, lack of appetite, nausea, vomiting, abdominal pain, dark urine, light stools, and/or yellowing of the skin or eyes, consult a doctor immediately. Do not stop using any medications without a doctor's advice.
PirfenidoneMipomersen
Severe
How does the drug interact with Pirfenex 200 mg Table:
Taking Mipomersen with Pirfenex 200 mg Table may increase the risk of liver damage.

How to manage the interaction:
Taking Pirfenex 200 mg Table with Mipomersen together can possibly result in an interaction, but it can be taken if your doctor has advised it. However, if you have any of the following symptoms: fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, fatigue, lack of appetite, nausea, vomiting, abdominal pain, dark urine, light stools, and/or yellowing of the skin or eyes, consult a doctor immediately. Do not discontinue any medications without a doctor's advice.
How does the drug interact with Pirfenex 200 mg Table:
Taking Pirfenex 200 mg Table with Rucaparib can increase the risk or severity of its side effects such as liver disease or gastric problems.

How to manage the interaction:
Co-administration of Pirfenex 200 mg Table with Rucaparib can possibly result in an interaction, but it can be taken if your doctor has advised it. However, if you have any of the following symptoms: fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, fatigue, lack of appetite, nausea, vomiting, abdominal pain, dark urine, light stools, and/or yellowing of the skin or eyes, consult a doctor immediately.
How does the drug interact with Pirfenex 200 mg Table:
When ciprofloxacin is taken Pirfenex 200 mg Table, the blood levels of Pirfenex 200 mg Table may increase, which may lead to side effects.

How to manage the interaction:
Although taking ciprofloxacin and Pirfenex 200 mg Table together can possibly result in an interaction, it can be taken if your doctor has prescribed it. However, if you have any of the following symptoms, fever, chills, joint pain or swelling, unusual bleeding or wounds, skin rash, itching, tiredness, nausea, vomiting, dark urine, light stools, and/or yellowing of the skin or eyes, consult a doctor. Do not discontinue any medications without a doctor's advice.
How does the drug interact with Pirfenex 200 mg Table:
When Pirfenex 200 mg Table is taken with Fluvoxamine, it can increase the risk of side effects.

How to manage the interaction:
Taking Pirfenex 200 mg Table with Fluvoxamine can possibly result in an interaction, but it can be taken if your doctor has advised it. However, if you have any of the following symptoms: fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, fatigue, lack of appetite, nausea, vomiting, abdominal pain, dark urine, light stools, and/or yellowing of the skin or eyes, consult a doctor immediately. Do not discontinue any medications without consulting a doctor.
PirfenidoneEnoxacin
Severe
How does the drug interact with Pirfenex 200 mg Table:
When Enoxacin is taken with Pirfenex 200 mg Table, it can increase the levels of Pirfenex 200 mg Table, which may lead to side effects.

How to manage the interaction:
Although taking Pirfenex 200 mg Table and Enoxacin together can cause an interaction, it can be taken if your doctor has suggested it. However, if you have any of the following symptoms: fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, fatigue, lack of appetite, nausea, vomiting, abdominal pain, dark urine, light stools, and/or yellowing of the skin or eyes, consult a doctor immediately. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

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PIRFENIDONE-200MGGrapefruit and Grapefruit Juice
Moderate

Drug-Food Interactions

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PIRFENIDONE-200MGGrapefruit and Grapefruit Juice
Moderate
Common Foods to Avoid:
Grapefruit Juice, Grapefruit

How to manage the interaction:
Taking grape fruit and its products while using Pirfenex 200 mg Table can increase the risk of side effects. Avoid grape fruit and its products during treatment with Pirfenex 200 mg Table.

Drug-Diseases Interactions

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No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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Drug-Drug Interactions Checker List

  • FLUVOXAMINE
  • CIPROFLOXACIN
  • ENOXACIN
  • RIFAMPICIN
  • AMIODARONE
  • PROPAFENONE
  • OMEPRAZOLE

Habit Forming

No

Special Advise

  • Your doctor may advise liver function tests prior to the start of the treatment.
  • Regular blood tests are advised at the start of treatment with Pirfenex 200 mg Table and monthly for every 6 months, and then for every 3 months thereafter to check the liver functioning.

Diet & Lifestyle Advise

  • Watch out for triggers that make the cough worse, such as smoke, foods, air-conditioning, high altitude, etc.
  • Exercise moderately. Eat healthily.
  • Follow the pulmonary rehabilitation program. It includes exercise, disease education, and group therapy.
  • Quit smoking.
  • Get ample rest.
  • Include green leafy vegetables, sweet potatoes, broccoli, tomatoes, carrots, mangoes, citrus fruits, berries, and cocoa.
  • Lean proteins such as fish, meat, and poultry are the best.
  • Hydration is important. Drink plenty of water, herbal tea, and fruit juices.
  • Avoid processed and refined foods.

Pirfenex 200 mg Table Substitute

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