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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Hari Kumar , MBBS
48 Hrs returnable
COD available

Online payment accepted

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Whats That

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Composition :

PIRFENIDONE-200MG

Manufacturer/Marketer :

Human Biolife India Pvt Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Therapeutic Class

MISCELLANEOUS

Country of origin

India
Other Info - PI96737

Author Details

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FAQs

Pirtenext 200mg Tablet helps in reducing the scarring and swelling in the lungs by decreasing the release/activity of naturally occurring growth factors in the body, thereby helps you breathe better.

Pirtenext 200mg Tablet might make you photosensitive (sensitivity to sunlight). Avoid exposure to sunlight and sunlamps. Wear SPF 50+ sunscreen and protective clothing to reduce exposure to sunlight. Talk to your doctor if you are taking any medicines known to cause photosensitivity. If you notice any symptoms of photosensitivity, consult a doctor.

Do not discontinue Pirtenext 200mg Tablet without consulting your doctor. To treat your condition effectually, continue taking Pirtenext 200mg Tablet for as long as prescribed. Do not be reluctant to speak with your doctor if you experience any difficulty while taking Pirtenext 200mg Tablet.

Diarrhoea might be a side-effect of Pirtenext 200mg Tablet. Drink lots of fluids and eat non-spicy food if you experience diarrhoea. If you find blood in stools (tarry stools) or if you have severe diarrhoea, consult your doctor. Do not take anti-diarrheal medicine on your own.

No, avoid smoking prior to the start of the treatment and while taking Pirtenext 200mg Tablet as smoking might alter the effectiveness of Pirtenext 200mg Tablet.

Weight loss could occur due to loss of appetite. Maintain proper weight by eating healthy food. Your doctor might monitor your weight whilst taking Pirtenext 200mg Tablet. Consult your doctor if you notice severe weight loss.

Disclaimer

While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.
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Alcohol

Caution

It is not known if alcohol interacts with Pirtenext 200mg Tablet. However, avoid consumption of alcohol while taking Pirtenext 200mg Tablet as it may cause increased dizziness.

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Pregnancy

Caution

Please consult your doctor if you have any concerns regarding this; your doctor will prescribe only if the benefits outweigh the risks.

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Breast Feeding

Caution

Consult your doctor if you are breastfeeding; your doctor will decide whether Pirtenext 200mg Tablet can be taken by breastfeeding mothers or not.

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Driving

Caution

Pirtenext 200mg Tablet might cause dizziness and tiredness. Drive or operate machinery only if you are alert.

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Liver

Caution

Dose adjustment may be needed. Please consult your doctor if you have a liver impairment or any concerns regarding this. Pirtenext 200mg Tablet is not recommended for patients with severe hepatic impairment.

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Kidney

Caution

Dose adjustment may be needed. Please consult your doctor if you have kidney impairment or any concerns. Pirtenext 200mg Tablet is not recommended for patients with an end-stage renal disease requiring dialysis.

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Children

Unsafe

Pirtenext 200mg Tablet is not recommended for children below 18years as the safety and effectiveness has not been established.

About Pirtenext 200mg Tablet

Pirtenext 200mg Tablet is an anti-fibrotic medicine used to treat idiopathic pulmonary fibrosis (IPF) in adults. IPF is an irreversible disease that is marked by a progressive decline in lung function. The tissues in the lungs become swollen and scarred over time, due to which it gets difficult to breathe deeply. The scarring makes it hard for the lungs to work properly.
 
Pirtenext 200mg Tablet contains ‘Pirfenidone’, which helps in reducing the scarring and swelling in the lungs by decreasing the release/activity of naturally occurring growth factors in the body, thereby helps you breathe better. Pirtenext 200mg Tablet helps in slowing down the progress of idiopathic pulmonary fibrosis. 

In some cases, you may experience certain common side effects such as nausea, tiredness, diarrhoea, indigestion, loss of appetite, headache, and photosensitivity. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side effects persistently.
 
Consult your doctor before taking Pirtenext 200mg Tablet if you are pregnant or breastfeeding. Pirtenext 200mg Tablet may cause tiredness and dizziness, so drive with caution. Avoid consuming alcohol with Pirtenext 200mg Tablet as it could lead to increased dizziness. Pirtenext 200mg Tablet is not recommended for children below 18 years as safety and effectiveness have not been established. Keep your doctor informed about your health condition and medicines to rule out any side effects.

Uses of Pirtenext 200mg Tablet

Idiopathic pulmonary fibrosis

Medicinal Benefits Mweb

Medicinal Benefits

Pirtenext 200mg Tablet is an anti-fibrotic medicine used to treat idiopathic pulmonary fibrosis (IPF) in adults. Pirtenext 200mg Tablet can help effectively slow the rate of lung function decline by 50%. Pirtenext 200mg Tablet helps reduce the scarring and swelling in the lungs by decreasing the release/activity of naturally occurring growth factors in the body, thereby helps you breathe better. Pirtenext 200mg Tablet helps in slowing down the progress of idiopathic pulmonary fibrosis.

Directions for Use

Take Pirtenext 200mg Tablet with food. Swallow Pirtenext 200mg Tablet as a whole with a glass of water; do not chew or crush it.

Side Effects of Pirtenext 200mg Tablet

  • Nausea
  • Tiredness
  • Diarrhoea
  • Indigestion/Stomach upset
  • Loss of appetite
  • Headache
  • Photosensitivity

Drug Warnings

Do not take Pirtenext 200mg Tablet if you are allergic to any of its components; if you have a severe or end-stage liver impairment or kidney disease requiring dialysis; if you are taking fluvoxamine (anti-depressant). Inform your doctor if you are taking any medicines that might make you photosensitive, if you smoke or have kidney or liver problems. Consult your doctor before taking Pirtenext 200mg Tablet if you are pregnant or breastfeeding. Pirtenext 200mg Tablet may cause tiredness and dizziness, so drive with caution. Avoid consuming alcohol with Pirtenext 200mg Tablet as it could lead to increased dizziness. Pirtenext 200mg Tablet is not recommended for children below 18 years as safety and effectiveness have not been established.

Drug-Drug Interactions

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PirfenidoneCarbamazepine
Critical
PirfenidonePrimidone
Critical

Drug-Drug Interactions

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PirfenidoneCarbamazepine
Critical
How does the drug interact with Pirtenext 200mg Tablet:
Taking Pirtenext 200mg Tablet with Carbamazepine it reduces the levels and effects of Pirtenext 200mg Tablet.

How to manage the interaction:
Taking Pirtenext 200mg Tablet with Carbamazepine is not recommended but can be taken if prescribed by the doctor. However, if you experience any unusual symptoms contact a doctor immediately. Do not stop using any medications without talking to a doctor.
PirfenidonePrimidone
Critical
How does the drug interact with Pirtenext 200mg Tablet:
Coadministration of Pirtenext 200mg Tablet with primidone can reduce levels and the effects of Pirtenext 200mg Tablet.

How to manage the interaction:
Although there is an interaction between Pirtenext 200mg Tablet and primidone, they can be taken together if advised by your doctor. However, if you experience any unusual symptoms, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
PirfenidonePhenobarbital
Critical
How does the drug interact with Pirtenext 200mg Tablet:
When Pirtenext 200mg Tablet is taken with Phenobarbital, it can decrease the effects of Pirtenext 200mg Tablet.

How to manage the interaction:
Taking Pirtenext 200mg Tablet with Phenobarbital is not recommended but can be taken if prescribed by the doctor. Do not discontinue any medication without consulting a doctor.
PirfenidoneRifampicin
Critical
How does the drug interact with Pirtenext 200mg Tablet:
Taking Pirtenext 200mg Tablet with rifampicin can reduce the levels and effects of Pirtenext 200mg Tablet

How to manage the interaction:
Although there is an interaction between Pirtenext 200mg Tablet and rifampicin, they can be taken together if prescribed by a doctor. However, if you experience any unusual symptoms, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
PirfenidoneCiprofloxacin
Severe
How does the drug interact with Pirtenext 200mg Tablet:
When ciprofloxacin is taken Pirtenext 200mg Tablet, the blood levels of Pirtenext 200mg Tablet may increase, which may lead to side effects.

How to manage the interaction:
Although taking ciprofloxacin and Pirtenext 200mg Tablet together can possibly result in an interaction, it can be taken if your doctor has prescribed it. However, if you have any of the following symptoms, fever, chills, joint pain or swelling, unusual bleeding or wounds, skin rash, itching, tiredness, nausea, vomiting, dark urine, light stools, and/or yellowing of the skin or eyes, consult a doctor. Do not discontinue any medications without a doctor's advice.
PirfenidoneKetoconazole
Severe
How does the drug interact with Pirtenext 200mg Tablet:
Coadministration of Ketoconazole and Pirtenext 200mg Tablet may increase the risk of liver damage.

How to manage the interaction:
Although taking Ketoconazole and Pirtenext 200mg Tablet together can result in an interaction, it can be taken if a doctor has prescribed it. However, if you have any of the following symptoms: fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, fatigue, lack of appetite, nausea, vomiting, abdominal pain, dark urine, light stools, and/or yellowing of the skin or eyes, consult the doctor immediately. Do not discontinue any medications without a doctor's advice.
PirfenidoneRucaparib
Severe
How does the drug interact with Pirtenext 200mg Tablet:
Taking Pirtenext 200mg Tablet with Rucaparib can increase the risk or severity of its side effects such as liver disease or gastric problems.

How to manage the interaction:
Co-administration of Pirtenext 200mg Tablet with Rucaparib can possibly result in an interaction, but it can be taken if your doctor has advised it. However, if you have any of the following symptoms: fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, fatigue, lack of appetite, nausea, vomiting, abdominal pain, dark urine, light stools, and/or yellowing of the skin or eyes, consult a doctor immediately.
PirfenidoneEnoxacin
Severe
How does the drug interact with Pirtenext 200mg Tablet:
When Enoxacin is taken with Pirtenext 200mg Tablet, it can increase the levels of Pirtenext 200mg Tablet, which may lead to side effects.

How to manage the interaction:
Although taking Pirtenext 200mg Tablet and Enoxacin together can cause an interaction, it can be taken if your doctor has suggested it. However, if you have any of the following symptoms: fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, fatigue, lack of appetite, nausea, vomiting, abdominal pain, dark urine, light stools, and/or yellowing of the skin or eyes, consult a doctor immediately. Do not discontinue any medications without consulting a doctor.
PirfenidoneAminolevulinic acid
Severe
How does the drug interact with Pirtenext 200mg Tablet:
Co-administration of Aminolevulinic acid and Pirtenext 200mg Tablet may increase the risk of skin burn.

How to manage the interaction:
There may be a possibility of interaction between Pirtenext 200mg Tablet and Aminolevulinic acid, but it can be taken if prescribed by a doctor. Avoid exposure of the eyes and skin to sunlight or bright indoor lights for 48 hours after treatment. Do not discontinue any medications without consulting a doctor.
PirfenidoneLeflunomide
Severe
How does the drug interact with Pirtenext 200mg Tablet:
Taking Leflunomide with Pirtenext 200mg Tablet may increase the risk of liver damage.

How to manage the interaction:
Co-administration of Pirtenext 200mg Tablet with Leflunomide can possibly result in an interaction, but it can be taken if your doctor has advised it. However, if you have any of the following symptoms: fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, fatigue, lack of appetite, nausea, vomiting, abdominal pain, dark urine, light stools, and/or yellowing of the skin or eyes, consult a doctor immediately. Do not stop using any medications without talking to a doctor.

Drug-Food Interactions

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PIRFENIDONE-200MGGrapefruit and Grapefruit Juice
Moderate

Drug-Food Interactions

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PIRFENIDONE-200MGGrapefruit and Grapefruit Juice
Moderate
Common Foods to Avoid:
Grapefruit Juice, Grapefruit

How to manage the interaction:
Taking grape fruit and its products while using Pirtenext 200mg Tablet can increase the risk of side effects. Avoid grape fruit and its products during treatment with Pirtenext 200mg Tablet.

Drug-Diseases Interactions

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No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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Drug-Drug Interactions Checker List

  • FLUVOXAMINE
  • CIPROFLOXACIN
  • ENOXACIN
  • RIFAMPICIN
  • AMIODARONE
  • PROPAFENONE
  • OMEPRAZOLE

Habit Forming

No

Special Advise

  • Your doctor may advise liver function tests prior to the start of the treatment.
  • Regular blood tests are advised at the start of treatment with Pirtenext 200mg Tablet and monthly for every 6 months, and then for every 3 months thereafter to check the liver functioning.

Diet & Lifestyle Advise

  • Watch out for triggers that make the cough worse, such as smoke, foods, air-conditioning, high altitude, etc.
  • Exercise moderately. Eat healthily.
  • Follow the pulmonary rehabilitation program. It includes exercise, disease education, and group therapy.
  • Quit smoking.
  • Get ample rest.
  • Include green leafy vegetables, sweet potatoes, broccoli, tomatoes, carrots, mangoes, citrus fruits, berries, and cocoa.
  • Lean proteins such as fish, meat, and poultry are the best.
  • Hydration is important. Drink plenty of water, herbal tea, and fruit juices.
  • Avoid processed and refined foods.

Pirtenext 200mg Tablet Substitute

Substitutes safety advice
  • Pirfenex 200 mg Table 15's

    by AYUR

    25.20per tablet
  • Fibrodone Tablet 10's

    by Others

    25.38per tablet
  • Pulmofib 200 mg Tablet 10's

    by AYUR

    21.96per tablet
  • Pirfetab 200 Tablet 10's

    by Others

    30.42per tablet
  • Ipf-Care Tablet

    by Others

    20.94per tablet
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