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  3. Renokinase 500000IU Injection

Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Santoshini Reddy G , M Pharmacy
48 Hrs returnable
COD available

Online payment accepted

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Whats That

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Composition :

UROKINASE-500000IU

Manufacturer/Marketer :

Biosena Life Sciences

Consume Type :

PARENTERAL

Return Policy :

Not Returnable

Therapeutic Class

ANTICOAGULANT/ANTITHROMBOTIC

Country of origin

India
Other Info - RE14887

Author Details

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FAQs

Renokinase 500000IU Injection works by dissolving the harmful blood clots in the blood vessels. This restores the blood flow to the affected blood vessels, preventing various illnesses caused by blood clots.

Yes, Renokinase 500000IU Injection raises the possibility of bleeding. Always exercise caution when engaging in activities that could result in an injury or bleeding. Notify your doctor right away if you notice any unusual bruises or bleeding.

To determine blood clotting time, tests such as platelet count, factor V assay, fibrinogen level test, prothrombin time test (PT or PT-INR), and the INR (international normalised ratio) are utilised.

If you are scheduled for surgery, please consult your doctor. The doctor may advise you to stop taking Renokinase 500000IU Injection a few days before surgery because it increases the chance of bleeding during surgery.

Renokinase 500000IU Injection is not recommended for use in people with severe uncontrolled high blood pressure.

Disclaimer

While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.
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Alcohol

Unsafe

Avoid the consumption of alcohol with Renokinase 500000IU Injection as it may increase the risk of bleeding.

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Pregnancy

Unsafe

Renokinase 500000IU Injection is not recommended during pregnancy or immediately after the delivery unless advised by the doctor. Please consult a doctor if you are pregnant or planning for pregnancy.

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Breast Feeding

Unsafe

Breastfeeding is not recommended during treatment with Renokinase 500000IU Injection. Please consult a doctor if you have any concerns.

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Driving

Caution

It is unclear whether Renokinase 500000IU Injection impacts your ability to drive or operate machinery. However, drive or operate machinery only if you are alert.

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Liver

Caution

Let your doctor know if you have a history of liver diseases/conditions. Your doctor will prescribe only if the benefits outweigh the risks.

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Kidney

Caution

Let your doctor know if you have a history of kidney diseases/conditions. Your doctor will prescribe only if the benefits outweigh the risks.

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Children

Unsafe

Renokinase 500000IU Injection is not recommended for children as safety and effectiveness have not been established.

About Renokinase 500000IU Injection

Renokinase 500000IU Injection belongs to a class of drugs called antithrombotic agents used to dissolve harmful blood clots in blood vessels. It is used in conditions such as peripheral vascular thromboembolism (blood clot in a large vein), cerebral thrombosis (blood clot in venous sinuses of the brain), cerebral infarction (stroke), myocardial infarction (heart attack),  and pulmonary embolism (blood clots in the lungs).

Renokinase 500000IU Injection contains urokinase that works by converting plasminogen to the enzyme plasmin. Plasmin degrades fibrin clots as well as fibrinogen and some other plasma proteins. It effectively dissolves the blood clots, restoring the blood flow to the affected area.

Renokinase 500000IU Injection will be administered by a healthcare professional. In some cases, Renokinase 500000IU Injection may cause unusual bleeding, nausea, vomiting, and loss of appetite. Most of these side effects do not necessitate medical treatment and fade away with time. Please visit your doctor if the side effects persist or worsen.

If you are pregnant or breastfeeding, inform your doctor before taking Renokinase 500000IU Injection. Keep your doctor updated on your medical condition and medications to rule out any potential interactions. Avoid consuming alcohol along with Renokinase 500000IU Injection as it could increase the risk of bleeding. Renokinase 500000IU Injection should not be given to children because its safety and effectiveness have not been proven.

Uses of Renokinase 500000IU Injection

Blood clots

Medicinal Benefits Mweb

Medicinal Benefits

Renokinase 500000IU Injection belongs to a class of drugs known as antithrombotic medications. Renokinase 500000IU Injection contains urokinase. It works by dissolving or lysing the harmful or unwanted blood clots in the blood vessels. Thus it restores the blood flow to the affected blood vessels, preventing various illnesses caused by blood clots. It is used in conditions such as peripheral vascular thromboembolism (blood clot in a large vein), cerebral thrombosis (blood clot in venous sinuses of the brain), cerebral infarction (stroke), myocardial infarction (heart attack),  and pulmonary embolism (blood clots in the lungs).

Directions for Use

Renokinase 500000IU Injection is given as an intravenous (into a vein) injection by a doctor or nurse. Do not self-administer.

Side Effects of Renokinase 500000IU Injection

  • Unusual bleeding
  • Nausea
  • Vomiting
  • Loss of appetite

Drug Warnings

Before taking Renokinase 500000IU Injection, tell your doctor if you are pregnant or breastfeeding. Renokinase 500000IU Injection should be used with caution in elderly people because they are at significant risk of bleeding. If you have active tuberculosis, stomach ulcers, severe uncontrolled arterial hypertension, bleeding abnormalities, severe hepatic or renal diseases, inform your doctor before taking Renokinase 500000IU Injection. Also, let your doctor know if you have had a recent cerebrovascular accident, as well as intracranial or intraspinal surgery. Inform your doctor that you take Renokinase 500000IU Injection if are due to undergo surgery. You should avoid alcohol because it increases the risk of bleeding. Renokinase 500000IU Injection is not recommended for children since its safety and effectiveness have not been proven.

Drug-Drug Interactions

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Drug-Drug Interactions

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How does the drug interact with Renokinase 500000IU Injection:
Co-administration of Renokinase 500000IU Injection with Cangrelo can enhance the blood-thinning effects of Cangrelor.

How to manage the interaction:
Although taking Renokinase 500000IU Injection and Cangrelor together can evidently cause an interaction, it can be taken if a doctor has suggested it. If you notice any of these signs, it's important to contact a doctor right away: bleeding, problems, bruising, feeling dizzy or lightheaded, stools that are red or black and sticky, intense headache, weakness, bleeding, or vomiting. Do not stop using any medications without a doctor's advice.
How does the drug interact with Renokinase 500000IU Injection:
Combining Dasatinib with Renokinase 500000IU Injection can increase the risk and severity of bleeding and hemorrhage.

How to manage the interaction:
Co-administration of Renokinase 500000IU Injection with Dasatinib can result in an interaction, but it can be taken if a doctor has advised it. If you notice any of these signs, it's important to contact a doctor right away: bleeding, problems, bruising, feeling dizzy or lightheaded, stools that are red or black and sticky, intense headache, weakness, bleeding, or vomiting. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Renokinase 500000IU Injection:
Coadministration of warfarin with Renokinase 500000IU Injection can increase the risk of bleeding.

How to manage the interaction:
Although taking Renokinase 500000IU Injection and warfarin together can result in an interaction, it can be taken if a doctor has prescribed it. However, if you experience unusual bleeding or bruising, dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness, consult a doctor. Do not stop using any medications without a doctor's advice.
How does the drug interact with Renokinase 500000IU Injection:
Co-administration of Prasugrel with Renokinase 500000IU Injection can increase the risk of bleeding leading to serious blood loss.

How to manage the interaction:
Although taking Prasugrel and Renokinase 500000IU Injection together can evidently cause an interaction, it can be taken if a doctor has suggested it. However, if you experience unusual bleeding or bruising, dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness, consult the doctor. Do not stop using any medications without a doctor's advice.
How does the drug interact with Renokinase 500000IU Injection:
Co-administration of Ibrutinib with Renokinase 500000IU Injection can increase the risk of bleeding leading to serious blood loss.

How to manage the interaction:
Taking Ibrutinib with Renokinase 500000IU Injection together can result in an interaction, but it can be taken if a doctor has advised it. However, if you experience unusual bleeding or bruising, dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness, consult a doctor. Do not stop using any medications without a doctor's advice.
How does the drug interact with Renokinase 500000IU Injection:
Coadministration of Renokinase 500000IU Injection and Apixaban co-administration may raise the risk of bleeding.

How to manage the interaction:
Even though combining Renokinase 500000IU Injection and Apixaban may cause an interaction, it is still possible to take it if your doctor advises you to. Consult a doctor if you experience symptoms like blood in your urine or stool (or a black stool), severe bruising, prolonged nosebleeds, feeling dizzy or lightheaded, weakness or severe headache, vomiting blood or coughing up blood, heavy menstrual bleeding (in women), difficulty breathing, or chest pain. Without consulting a doctor, never stop taking any medications.
How does the drug interact with Renokinase 500000IU Injection:
Taking Dabigatran etexilate with Renokinase 500000IU Injection can increase the risk of bleeding leading to serious blood loss.

How to manage the interaction:
Taking Dabigatran etexilate with Renokinase 500000IU Injection together can possibly result in an interaction, but it can be taken if your doctor has advised it. However, if you experience unusual bleeding or bruising, dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness, consult the doctor. Do not stop using any medications without a doctor's advice.
How does the drug interact with Renokinase 500000IU Injection:
Combining Renokinase 500000IU Injection with Dalteparin can increase the risk of bleeding.

How to manage the interaction:
Although taking Dalteparin with Renokinase 500000IU Injection may possibly lead to an interaction, they can be taken if a doctor prescribes it. Consult a doctor if you have any symptoms including dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that resembles coffee grounds, severe headache, and weakness. Without consulting a doctor, never stop taking any medication.
How does the drug interact with Renokinase 500000IU Injection:
Taking Renokinase 500000IU Injection with fondaparinux can increase the risk of bleeding.

How to manage the interaction:
Although there is an interaction between Fondaparinux and Renokinase 500000IU Injection, they can be taken together if prescribed by a doctor. However, consult a doctor if you experience bleeding, severe back pain, dizziness, black or red stools, severe headache, weakness, and vomiting. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Renokinase 500000IU Injection:
Taking Heparin with Renokinase 500000IU Injection can increase the risk of bleeding.

How to manage the interaction:
Co-administration of Heparin with Renokinase 500000IU Injection can result in an interaction, but it can be taken if a doctor has advised it. However, if you have unusual bleeding or bruising, vomiting, blood in your urine or stools, headache, dizziness, or weakness, consult a doctor immediately. Do not stop using any medications without a doctor's advice.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Drug-Diseases Interactions

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No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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Drug-Drug Interactions Checker List

  • WARFARIN
  • ASPIRIN
  • TICLOPIDINE HYDROCHLORIDE
  • DIPYRIDAMOLE

Habit Forming

No

Diet & Lifestyle Advise

  • Avoid cranberry juice, grapefruit juice, noni juice, pomegranate juice, and green tea.
  • Make no dietary changes without first consulting your doctor.
  • You should avoid alcohol because it increases the risk of bleeding.
  • Maintain a healthy cholesterol and triglyceride level.
  • Maintain a healthy weight and exercise routine to keep your heart healthy.

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