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  3. Solokinase 500000IU Injection

Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Santoshini Reddy G , M Pharmacy
Non returnable*
COD available

Online payment accepted

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Composition :

UROKINASE-500000IU

Manufacturer/Marketer :

Aristo Pharmaceuticals Pvt Ltd

Consume Type :

PARENTERAL

Return Policy :

Not Returnable

About Solokinase 500000IU Injection

Solokinase 500000IU Injection belongs to a class of drugs called antithrombotic agents used to dissolve harmful blood clots in blood vessels. It is used in conditions such as peripheral vascular thromboembolism (blood clot in a large vein), cerebral thrombosis (blood clot in venous sinuses of the brain), cerebral infarction (stroke), myocardial infarction (heart attack),  and pulmonary embolism (blood clots in the lungs).

Solokinase 500000IU Injection contains urokinase that works by converting plasminogen to the enzyme plasmin. Plasmin degrades fibrin clots as well as fibrinogen and some other plasma proteins. It effectively dissolves the blood clots, restoring the blood flow to the affected area.

Solokinase 500000IU Injection will be administered by a healthcare professional. In some cases, Solokinase 500000IU Injection may cause unusual bleeding, nausea, vomiting, and loss of appetite. Most of these side effects do not necessitate medical treatment and fade away with time. Please visit your doctor if the side effects persist or worsen.

If you are pregnant or breastfeeding, inform your doctor before taking Solokinase 500000IU Injection. Keep your doctor updated on your medical condition and medications to rule out any potential interactions. Avoid consuming alcohol along with Solokinase 500000IU Injection as it could increase the risk of bleeding. Solokinase 500000IU Injection should not be given to children because its safety and effectiveness have not been proven.

Uses of Solokinase 500000IU Injection

Blood clots

Directions for Use

Solokinase 500000IU Injection is given as an intravenous (into a vein) injection by a doctor or nurse. Do not self-administer.

Medicinal Benefits

Solokinase 500000IU Injection belongs to a class of drugs known as antithrombotic medications. Solokinase 500000IU Injection contains urokinase. It works by dissolving or lysing the harmful or unwanted blood clots in the blood vessels. Thus it restores the blood flow to the affected blood vessels, preventing various illnesses caused by blood clots. It is used in conditions such as peripheral vascular thromboembolism (blood clot in a large vein), cerebral thrombosis (blood clot in venous sinuses of the brain), cerebral infarction (stroke), myocardial infarction (heart attack),  and pulmonary embolism (blood clots in the lungs).

Storage

Store in a cool and dry place away from sunlight

Drug Warnings

Before taking Solokinase 500000IU Injection, tell your doctor if you are pregnant or breastfeeding. Solokinase 500000IU Injection should be used with caution in elderly people because they are at significant risk of bleeding. If you have active tuberculosis, stomach ulcers, severe uncontrolled arterial hypertension, bleeding abnormalities, severe hepatic or renal diseases, inform your doctor before taking Solokinase 500000IU Injection. Also, let your doctor know if you have had a recent cerebrovascular accident, as well as intracranial or intraspinal surgery. Inform your doctor that you take Solokinase 500000IU Injection if are due to undergo surgery. You should avoid alcohol because it increases the risk of bleeding. Solokinase 500000IU Injection is not recommended for children since its safety and effectiveness have not been proven.

Drug-Drug Interactions

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Drug-Drug Interactions

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How does the drug interact with Solokinase 500000IU Injection:
Co-administration of Solokinase 500000IU Injection and Rivaroxaban can increase the risk of bleeding problems.

How to manage the interaction:
Co-administration of Solokinase 500000IU Injection and Rivaroxaban can lead to an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like unusual bleeding or bruising, dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness, consult the doctor immediately. Do not stop using any medications without a doctor's advice.
How does the drug interact with Solokinase 500000IU Injection:
Coadministration of Solokinase 500000IU Injection and Apixaban co-administration may raise the risk of bleeding.

How to manage the interaction:
Even though combining Solokinase 500000IU Injection and Apixaban may cause an interaction, it is still possible to take it if your doctor advises you to. Consult a doctor if you experience symptoms like blood in your urine or stool (or a black stool), severe bruising, prolonged nosebleeds, feeling dizzy or lightheaded, weakness or severe headache, vomiting blood or coughing up blood, heavy menstrual bleeding (in women), difficulty breathing, or chest pain. Without consulting a doctor, never stop taking any medications.
How does the drug interact with Solokinase 500000IU Injection:
Co-administration of Ibrutinib with Solokinase 500000IU Injection can increase the risk of bleeding leading to serious blood loss.

How to manage the interaction:
Taking Ibrutinib with Solokinase 500000IU Injection together can result in an interaction, but it can be taken if a doctor has advised it. However, if you experience unusual bleeding or bruising, dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness, consult a doctor. Do not stop using any medications without a doctor's advice.
How does the drug interact with Solokinase 500000IU Injection:
Co-administration of Prasugrel with Solokinase 500000IU Injection can increase the risk of bleeding leading to serious blood loss.

How to manage the interaction:
Although taking Prasugrel and Solokinase 500000IU Injection together can evidently cause an interaction, it can be taken if a doctor has suggested it. However, if you experience unusual bleeding or bruising, dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness, consult the doctor. Do not stop using any medications without a doctor's advice.
How does the drug interact with Solokinase 500000IU Injection:
Combining Dasatinib with Solokinase 500000IU Injection can increase the risk and severity of bleeding and hemorrhage.

How to manage the interaction:
Co-administration of Solokinase 500000IU Injection with Dasatinib can result in an interaction, but it can be taken if a doctor has advised it. If you notice any of these signs, it's important to contact a doctor right away: bleeding, problems, bruising, feeling dizzy or lightheaded, stools that are red or black and sticky, intense headache, weakness, bleeding, or vomiting. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Solokinase 500000IU Injection:
Combining Solokinase 500000IU Injection with Dalteparin can increase the risk of bleeding.

How to manage the interaction:
Although taking Dalteparin with Solokinase 500000IU Injection may possibly lead to an interaction, they can be taken if a doctor prescribes it. Consult a doctor if you have any symptoms including dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that resembles coffee grounds, severe headache, and weakness. Without consulting a doctor, never stop taking any medication.
How does the drug interact with Solokinase 500000IU Injection:
Taking Solokinase 500000IU Injection with Enoxaparin can increase the risk or severity of bleeding.

How to manage the interaction:
Although there is a possible interaction between Enoxaparin and Solokinase 500000IU Injection, you can take these medicines together if prescribed by your doctor. If you notice any symptoms like bleeding, bruising, dizziness, black or tarry stools, weakness, vomiting, or headaches, it is important to contact a doctor right away. Do not stop using any medications without talking to a doctor.
How does the drug interact with Solokinase 500000IU Injection:
Taking Heparin with Solokinase 500000IU Injection can increase the risk of bleeding.

How to manage the interaction:
Co-administration of Heparin with Solokinase 500000IU Injection can result in an interaction, but it can be taken if a doctor has advised it. However, if you have unusual bleeding or bruising, vomiting, blood in your urine or stools, headache, dizziness, or weakness, consult a doctor immediately. Do not stop using any medications without a doctor's advice.
How does the drug interact with Solokinase 500000IU Injection:
Co-administration of Solokinase 500000IU Injection with Cangrelo can enhance the blood-thinning effects of Cangrelor.

How to manage the interaction:
Although taking Solokinase 500000IU Injection and Cangrelor together can evidently cause an interaction, it can be taken if a doctor has suggested it. If you notice any of these signs, it's important to contact a doctor right away: bleeding, problems, bruising, feeling dizzy or lightheaded, stools that are red or black and sticky, intense headache, weakness, bleeding, or vomiting. Do not stop using any medications without a doctor's advice.
How does the drug interact with Solokinase 500000IU Injection:
Taking Dabigatran etexilate with Solokinase 500000IU Injection can increase the risk of bleeding leading to serious blood loss.

How to manage the interaction:
Taking Dabigatran etexilate with Solokinase 500000IU Injection together can possibly result in an interaction, but it can be taken if your doctor has advised it. However, if you experience unusual bleeding or bruising, dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness, consult the doctor. Do not stop using any medications without a doctor's advice.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Avoid cranberry juice, grapefruit juice, noni juice, pomegranate juice, and green tea.
  • Make no dietary changes without first consulting your doctor.
  • You should avoid alcohol because it increases the risk of bleeding.
  • Maintain a healthy cholesterol and triglyceride level.
  • Maintain a healthy weight and exercise routine to keep your heart healthy.

Habit Forming

No

Therapeutic Class

ANTICOAGULANT/ANTITHROMBOTIC

Author Details

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Drug-Diseases Interactions

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No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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FAQs

Solokinase 500000IU Injection works by dissolving the harmful blood clots in the blood vessels. This restores the blood flow to the affected blood vessels, preventing various illnesses caused by blood clots.

Yes, Solokinase 500000IU Injection raises the possibility of bleeding. Always exercise caution when engaging in activities that could result in an injury or bleeding. Notify your doctor right away if you notice any unusual bruises or bleeding.

To determine blood clotting time, tests such as platelet count, factor V assay, fibrinogen level test, prothrombin time test (PT or PT-INR), and the INR (international normalised ratio) are utilised.

If you are scheduled for surgery, please consult your doctor. The doctor may advise you to stop taking Solokinase 500000IU Injection a few days before surgery because it increases the chance of bleeding during surgery.

Solokinase 500000IU Injection is not recommended for use in people with severe uncontrolled high blood pressure.

Drug-Drug Interactions Checker List

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Disease/Condition Glossary

Blood Clot: A blood clot is a clump or mass of blood formed when platelets, proteins, and cells in the blood adhere to one another. When you are injured, your body creates a blood clot to stop the bleeding. Though blood clots are helpful to stop bleeding, they may be harmful when abnormally formed within blood vessels as they block blood vessels and inhibit blood flow to essential organs such as the brain, heart or lungs and result in severe conditions. Obesity, smoking, cancer, a family history of blood clots, age over 65, and certain birth control pills or pregnancy are common risk factors for blood clots.

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