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Composition :
GLIBENCLAMIDE-2.5MG
Manufacturer/Marketer :
Emcure Pharmaceuticals Ltd
Consume Type :
Oral
Expires on or after :
Return Policy :
Not Returnable
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Product Substitutes
Drug-Drug Interactions
Severe
Drug-Drug Interactions
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How does the drug interact with Semi Daonil 2.5mg Tablet:
Co-administration of Nalidixic acid can affect blood glucose levels. Both high blood glucose and, less frequently, low blood glucose have been reported.
How to manage the interaction:
Although there is a possible interaction, Semi Daonil 2.5mg Tablet can be taken with Nalidixic acid if prescribed by the doctor. Consult the prescriber if you experience symptoms of low blood sugar such as nervousness, confusion, headache, dizziness, drowsiness, tremor, nausea, hunger, weakness, perspiration, palpitation, and rapid heartbeat or symptoms of high blood sugar such as increased urination, increased thirst, and increased hunger. Monitoring of blood glucose levels is advised. Do not discontinue any medications without consulting a doctor.
Co-administration of Nalidixic acid can affect blood glucose levels. Both high blood glucose and, less frequently, low blood glucose have been reported.
How to manage the interaction:
Although there is a possible interaction, Semi Daonil 2.5mg Tablet can be taken with Nalidixic acid if prescribed by the doctor. Consult the prescriber if you experience symptoms of low blood sugar such as nervousness, confusion, headache, dizziness, drowsiness, tremor, nausea, hunger, weakness, perspiration, palpitation, and rapid heartbeat or symptoms of high blood sugar such as increased urination, increased thirst, and increased hunger. Monitoring of blood glucose levels is advised. Do not discontinue any medications without consulting a doctor.
Severe
How does the drug interact with Semi Daonil 2.5mg Tablet:
Co-administration of Ofloxacin with Semi Daonil 2.5mg Tablet can sometimes affect blood glucose levels. Both high blood glucose and, less frequently, low blood glucose have been reported.
How to manage the interaction:
Although there is a possible interaction, Semi Daonil 2.5mg Tablet can be taken with Ofloxacin if prescribed by the doctor. Consult the prescriber if you experience symptoms of low blood sugar such as nervousness, confusion, headache, dizziness, drowsiness, tremor, nausea, hunger, weakness, perspiration, palpitation, and rapid heartbeat or symptoms of high blood sugar such as increased urination, increased thirst, and increased hunger. Maintaining blood glucose levels is advised. Do not discontinue the medications without consulting a doctor.
Co-administration of Ofloxacin with Semi Daonil 2.5mg Tablet can sometimes affect blood glucose levels. Both high blood glucose and, less frequently, low blood glucose have been reported.
How to manage the interaction:
Although there is a possible interaction, Semi Daonil 2.5mg Tablet can be taken with Ofloxacin if prescribed by the doctor. Consult the prescriber if you experience symptoms of low blood sugar such as nervousness, confusion, headache, dizziness, drowsiness, tremor, nausea, hunger, weakness, perspiration, palpitation, and rapid heartbeat or symptoms of high blood sugar such as increased urination, increased thirst, and increased hunger. Maintaining blood glucose levels is advised. Do not discontinue the medications without consulting a doctor.
Severe
How does the drug interact with Semi Daonil 2.5mg Tablet:
Co-administration of Norfloxacin with Semi Daonil 2.5mg Tablet may sometimes affect blood glucose levels. Both high blood glucose and, less frequently, low blood glucose have been reported.
How to manage the interaction:
Although there is a possible interaction, Semi Daonil 2.5mg Tablet can be taken with Norfloxacin if prescribed by the doctor. Consult the prescriber if you experience symptoms of low blood sugar such as nervousness, confusion, headache, dizziness, drowsiness, tremor, nausea, hunger, weakness, perspiration, palpitation, and rapid heartbeat or symptoms of high blood sugar such as increased urination, increased thirst, and increased hunger. Maintaining blood glucose levels is advised. Do not discontinue any medications without consulting a doctor.
Co-administration of Norfloxacin with Semi Daonil 2.5mg Tablet may sometimes affect blood glucose levels. Both high blood glucose and, less frequently, low blood glucose have been reported.
How to manage the interaction:
Although there is a possible interaction, Semi Daonil 2.5mg Tablet can be taken with Norfloxacin if prescribed by the doctor. Consult the prescriber if you experience symptoms of low blood sugar such as nervousness, confusion, headache, dizziness, drowsiness, tremor, nausea, hunger, weakness, perspiration, palpitation, and rapid heartbeat or symptoms of high blood sugar such as increased urination, increased thirst, and increased hunger. Maintaining blood glucose levels is advised. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Semi Daonil 2.5mg Tablet:
Co-administration of Sparfloxacin can sometimes affect blood glucose levels. Both high blood glucose and, less frequently, low blood glucose have been reported.
How to manage the interaction:
Although there is a possible interaction, Semi Daonil 2.5mg Tablet can be taken with sparfloxacin if prescribed by the doctor. Consult the prescriber if you experience symptoms of low blood sugar such as nervousness, confusion, headache, dizziness, drowsiness, tremor, nausea, hunger, weakness, perspiration, palpitation, and rapid heartbeat or symptoms of high blood sugar such as increased urination, increased thirst, and increased hunger. Do not discontinue the medications without consulting a doctor.
Co-administration of Sparfloxacin can sometimes affect blood glucose levels. Both high blood glucose and, less frequently, low blood glucose have been reported.
How to manage the interaction:
Although there is a possible interaction, Semi Daonil 2.5mg Tablet can be taken with sparfloxacin if prescribed by the doctor. Consult the prescriber if you experience symptoms of low blood sugar such as nervousness, confusion, headache, dizziness, drowsiness, tremor, nausea, hunger, weakness, perspiration, palpitation, and rapid heartbeat or symptoms of high blood sugar such as increased urination, increased thirst, and increased hunger. Do not discontinue the medications without consulting a doctor.
How does the drug interact with Semi Daonil 2.5mg Tablet:
Co-administration of Moxifloxacin may affect blood glucose levels. Both high blood glucose and low blood glucose.
How to manage the interaction:
Although there is a possible interaction, Semi Daonil 2.5mg Tablet can be taken with Moxifloxacin if prescribed by the doctor. Consult the prescriber if you experience headache, dizziness, rapid heartbeat, increased urination, increased thirst, and increased hunger. Do not discontinue the medications without consulting a doctor.
Co-administration of Moxifloxacin may affect blood glucose levels. Both high blood glucose and low blood glucose.
How to manage the interaction:
Although there is a possible interaction, Semi Daonil 2.5mg Tablet can be taken with Moxifloxacin if prescribed by the doctor. Consult the prescriber if you experience headache, dizziness, rapid heartbeat, increased urination, increased thirst, and increased hunger. Do not discontinue the medications without consulting a doctor.
GlibenclamideGrepafloxacin
Severe
How does the drug interact with Semi Daonil 2.5mg Tablet:
Co-administration of Semi Daonil 2.5mg Tablet with Grepafloxacin can sometimes affect blood glucose levels. Both hyperglycemia (high blood glucose) and, less frequently, hypoglycemia (low blood glucose) have been reported.
How to manage the interaction:
Co-administration of Semi Daonil 2.5mg Tablet with Grepafloxacin can possibly result in an interaction, but it can be taken if a doctor has advised it. If you experience any of these symptoms - severe infections, headaches, dizziness, drowsiness, confusion, trembling, nausea, hunger, weakness, fast heartbeat, or excessive thirst - it's best to call a doctor right away. Do not discontinue any medications without consulting a doctor.
Co-administration of Semi Daonil 2.5mg Tablet with Grepafloxacin can sometimes affect blood glucose levels. Both hyperglycemia (high blood glucose) and, less frequently, hypoglycemia (low blood glucose) have been reported.
How to manage the interaction:
Co-administration of Semi Daonil 2.5mg Tablet with Grepafloxacin can possibly result in an interaction, but it can be taken if a doctor has advised it. If you experience any of these symptoms - severe infections, headaches, dizziness, drowsiness, confusion, trembling, nausea, hunger, weakness, fast heartbeat, or excessive thirst - it's best to call a doctor right away. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Semi Daonil 2.5mg Tablet:
Co-administration of Semi Daonil 2.5mg Tablet with Ciprofloxacin may affect blood glucose levels leading to high blood glucose levels, and less frequently low blood glucose levels.
How to manage the interaction:
Although there is a possible interaction, Semi Daonil 2.5mg Tablet can be taken with Ciprofloxacin if prescribed by the doctor. Consult the doctor if you experience symptoms such as headache, dizziness, drowsiness, nervousness, confusion, tremor(shaking), nausea, hunger, weakness, sweating, rapid heartbeat, increased thirst, increased hunger, and increased urination. Do not discontinue the medications without consulting a doctor.
Co-administration of Semi Daonil 2.5mg Tablet with Ciprofloxacin may affect blood glucose levels leading to high blood glucose levels, and less frequently low blood glucose levels.
How to manage the interaction:
Although there is a possible interaction, Semi Daonil 2.5mg Tablet can be taken with Ciprofloxacin if prescribed by the doctor. Consult the doctor if you experience symptoms such as headache, dizziness, drowsiness, nervousness, confusion, tremor(shaking), nausea, hunger, weakness, sweating, rapid heartbeat, increased thirst, increased hunger, and increased urination. Do not discontinue the medications without consulting a doctor.
GlibenclamideLomefloxacin
Severe
How does the drug interact with Semi Daonil 2.5mg Tablet:
Co-administration of Lomefloxacin may sometimes affect blood glucose levels. Both high blood glucose and, less frequently, low blood glucose have been reported.
How to manage the interaction:
Although there is a possible interaction, Semi Daonil 2.5mg Tablet can be taken with lomefloxacin if prescribed by the doctor. Consult the prescriber if you experience symptoms of low blood sugar such as nervousness, confusion, headache, dizziness, drowsiness, tremor, nausea, hunger, weakness, perspiration, palpitation, and rapid heartbeat or symptoms of high blood sugar such as increased urination, increased thirst, and increased hunger. Monitoring of blood glucose levels is advised. Do not discontinue the medications without consulting a doctor.
Co-administration of Lomefloxacin may sometimes affect blood glucose levels. Both high blood glucose and, less frequently, low blood glucose have been reported.
How to manage the interaction:
Although there is a possible interaction, Semi Daonil 2.5mg Tablet can be taken with lomefloxacin if prescribed by the doctor. Consult the prescriber if you experience symptoms of low blood sugar such as nervousness, confusion, headache, dizziness, drowsiness, tremor, nausea, hunger, weakness, perspiration, palpitation, and rapid heartbeat or symptoms of high blood sugar such as increased urination, increased thirst, and increased hunger. Monitoring of blood glucose levels is advised. Do not discontinue the medications without consulting a doctor.
How does the drug interact with Semi Daonil 2.5mg Tablet:
Co-administration of Levofloxacin with Semi Daonil 2.5mg Tablet may affect blood glucose levels.
How to manage the interaction:
Although there is a possible interaction, Semi Daonil 2.5mg Tablet can be taken with levofloxacin if prescribed by the doctor. Consult the prescriber if you experience nervousness, confusion, headache, dizziness, drowsiness, tremors, nausea, hunger, weakness, perspiration, pulse, rapid heartbeat, increased urination, increased thirst, and increased hunger. Monitoring of blood glucose levels is advised. Do not discontinue the medications without consulting a doctor.
Co-administration of Levofloxacin with Semi Daonil 2.5mg Tablet may affect blood glucose levels.
How to manage the interaction:
Although there is a possible interaction, Semi Daonil 2.5mg Tablet can be taken with levofloxacin if prescribed by the doctor. Consult the prescriber if you experience nervousness, confusion, headache, dizziness, drowsiness, tremors, nausea, hunger, weakness, perspiration, pulse, rapid heartbeat, increased urination, increased thirst, and increased hunger. Monitoring of blood glucose levels is advised. Do not discontinue the medications without consulting a doctor.
GlibenclamideCinoxacin
Severe
How does the drug interact with Semi Daonil 2.5mg Tablet:
Co-administration of Semi Daonil 2.5mg Tablet with Cinoxacin can sometimes affect blood glucose levels. Both hyperglycemia (high blood glucose) and, less frequently, hypoglycemia (low blood glucose) have been reported.
How to manage the interaction:
Co-administration of Semi Daonil 2.5mg Tablet with Cinoxacin can possibly result in an interaction, but it can be taken if a doctor has advised it. It's important to keep an eye on your urination and if you notice any changes, let your doctor know. If you experience any of these symptoms - high or low blood sugar, severe infections, headaches, dizziness, confusion, or feeling shaky, make sure to call a doctor right away. Do not discontinue any medications without consulting a doctor.
Co-administration of Semi Daonil 2.5mg Tablet with Cinoxacin can sometimes affect blood glucose levels. Both hyperglycemia (high blood glucose) and, less frequently, hypoglycemia (low blood glucose) have been reported.
How to manage the interaction:
Co-administration of Semi Daonil 2.5mg Tablet with Cinoxacin can possibly result in an interaction, but it can be taken if a doctor has advised it. It's important to keep an eye on your urination and if you notice any changes, let your doctor know. If you experience any of these symptoms - high or low blood sugar, severe infections, headaches, dizziness, confusion, or feeling shaky, make sure to call a doctor right away. Do not discontinue any medications without consulting a doctor.
Drug-Food Interactions
No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.
Drug-Food Interactions
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Drug-Diseases Interactions
GLIBENCLAMIDE-2.5MGComplications and ill-defined descriptions of heart disease
Severe
GLIBENCLAMIDE-2.5MGOther diseases of liver
Severe
Drug-Diseases Interactions
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GLIBENCLAMIDE-2.5MGComplications and ill-defined descriptions of heart disease
Severe
How does the disease interact with Semi Daonil 2.5mg Tablet:
Compared to diet alone or diet plus insulin, the use of oral hypoglycemic medicines may be linked to a higher risk of cardiovascular mortality. The University Group Diabetes Programme (UGDP) project, a lengthy prospective clinical trial created to assess the efficacy of glucose-lowering medications in preventing or postponing vascular problems in individuals with non-insulin-dependent diabetes, is the basis for this warning. Since the cardiovascular death rate was almost 2.5 times higher in patients receiving diet plus a fixed dosage of either tolbutamide (a sulfonylurea) or phenformin (a biguanide) for 5 to 8 years, both of these therapies were stopped in the research. Despite disagreements surrounding how to interpret these findings, physicians and patients should be aware of the possibility
How to manage the interaction:
Oral hypoglycemic agents may be associated with an increased risk of heart problems. Let the doctor know if you have heart problems.
Compared to diet alone or diet plus insulin, the use of oral hypoglycemic medicines may be linked to a higher risk of cardiovascular mortality. The University Group Diabetes Programme (UGDP) project, a lengthy prospective clinical trial created to assess the efficacy of glucose-lowering medications in preventing or postponing vascular problems in individuals with non-insulin-dependent diabetes, is the basis for this warning. Since the cardiovascular death rate was almost 2.5 times higher in patients receiving diet plus a fixed dosage of either tolbutamide (a sulfonylurea) or phenformin (a biguanide) for 5 to 8 years, both of these therapies were stopped in the research. Despite disagreements surrounding how to interpret these findings, physicians and patients should be aware of the possibility
How to manage the interaction:
Oral hypoglycemic agents may be associated with an increased risk of heart problems. Let the doctor know if you have heart problems.
GLIBENCLAMIDE-2.5MGOther diseases of liver
Severe
How does the disease interact with Semi Daonil 2.5mg Tablet:
sulfonylureas are metabolized in the liver, and their metabolites (some with pharmacologic activity) are excreted in the urine and feces. Patients with impaired liver and/or renal function treated with sulfonylureas may be exposed to higher serum drug concentrations, which can increase the potential for severe hypoglycemic episodes induced by these agents. In the presence of hepatic impairment, gluconeogenic capacity may also be diminished, further compounding the risk. Therapy with sulfonylureas should be administered cautiously in patients with liver and/or renal disease. Reduced dosages and longer intervals between dosage adjustments may be required. Hypoglycemia, if it occurs during treatment, may be prolonged in these patients because of slowed metabolism and/or excretion of the drugs.
How to manage the interaction:
Therapy with sulfonylureas should be administered cautiously in patients with liver disease.
sulfonylureas are metabolized in the liver, and their metabolites (some with pharmacologic activity) are excreted in the urine and feces. Patients with impaired liver and/or renal function treated with sulfonylureas may be exposed to higher serum drug concentrations, which can increase the potential for severe hypoglycemic episodes induced by these agents. In the presence of hepatic impairment, gluconeogenic capacity may also be diminished, further compounding the risk. Therapy with sulfonylureas should be administered cautiously in patients with liver and/or renal disease. Reduced dosages and longer intervals between dosage adjustments may be required. Hypoglycemia, if it occurs during treatment, may be prolonged in these patients because of slowed metabolism and/or excretion of the drugs.
How to manage the interaction:
Therapy with sulfonylureas should be administered cautiously in patients with liver disease.
GLIBENCLAMIDE-2.5MGOther disorders of pancreatic internal secretion
Moderate
How does the disease interact with Semi Daonil 2.5mg Tablet:
When receiving therapy with insulin and/or oral hypoglycemic medications, hypoglycemia can frequently happen. Patients who may be particularly vulnerable to the onset of hypoglycemic episodes while taking these medications include those who are weak or malnourished, those who have faulty counterregulatory mechanisms (such as autonomic neuropathy and adrenal or pituitary insufficiency), and those who are taking beta-adrenergic blocking medications.
How to manage the interaction:
During treatment with oral hypoglycemic agents low blood sugar may commonly occur. Caution is advised in patients who may be particularly susceptible to the development of hypoglycemic episodes, including those who are weak or malnourished, those with autonomic neuropathy and adrenal or pituitary insufficiency, and those receiving beta-adrenergic blocking agents.
When receiving therapy with insulin and/or oral hypoglycemic medications, hypoglycemia can frequently happen. Patients who may be particularly vulnerable to the onset of hypoglycemic episodes while taking these medications include those who are weak or malnourished, those who have faulty counterregulatory mechanisms (such as autonomic neuropathy and adrenal or pituitary insufficiency), and those who are taking beta-adrenergic blocking medications.
How to manage the interaction:
During treatment with oral hypoglycemic agents low blood sugar may commonly occur. Caution is advised in patients who may be particularly susceptible to the development of hypoglycemic episodes, including those who are weak or malnourished, those with autonomic neuropathy and adrenal or pituitary insufficiency, and those receiving beta-adrenergic blocking agents.
GLIBENCLAMIDE-2.5MGAnaemia due to enzyme disorders
Moderate
How does the disease interact with Semi Daonil 2.5mg Tablet:
In people who lack the enzyme glucose 6-phosphate dehydrogenase (G6PD), sulfonylureas can lead to hemolytic anaemia. Patients with G6PD deficiency should use these medications with caution and may want to look for non-sulfonylurea alternatives. Following the launch of these medications, reports of hemolytic anaemia in people who had no known G6PD deficiency were made.
How to manage the interaction:
Therapy should be used with caution in patients with glucose 6-phosphate dehydrogenase (G6PD) deficiency and the use of a non-sulfonylurea alternative should be considered as sulfonylureas may cause hemolytic anemia in patients with G6PD deficiency.
In people who lack the enzyme glucose 6-phosphate dehydrogenase (G6PD), sulfonylureas can lead to hemolytic anaemia. Patients with G6PD deficiency should use these medications with caution and may want to look for non-sulfonylurea alternatives. Following the launch of these medications, reports of hemolytic anaemia in people who had no known G6PD deficiency were made.
How to manage the interaction:
Therapy should be used with caution in patients with glucose 6-phosphate dehydrogenase (G6PD) deficiency and the use of a non-sulfonylurea alternative should be considered as sulfonylureas may cause hemolytic anemia in patients with G6PD deficiency.
GLIBENCLAMIDE-2.5MGOther disorders of fluid, electrolyte and acid-base balance
Moderate
How does the disease interact with Semi Daonil 2.5mg Tablet:
In individuals who are taking other drugs, have medical problems that are known to induce hyponatremia, or have conditions that promote the release of antidiuretic hormone, treatment with sulfonylureas may result in hyponatremia. Certain sulfonylureas have been linked to the syndrome of inappropriate antidiuretic hormone (SIADH) secretion, and these medications may enhance the peripheral (antidiuretic) action of ADH or increase ADH release. Patients with hyponatremia or those who are more likely to develop it, such as the elderly, those on diuretics, or those who are volume-depleted, should be treated with caution.
How to manage the interaction:
Treatment with sulfonylureas may cause hyponatremia (low sodium level), in patients who are on other medications or have medical conditions known to cause hyponatremia or increase release of antidiuretic hormone. Caution should be used when treating patients with hyponatremia or at greater risk of developing hyponatremia such as elderly patients, patients taking diuretics or those who are volume-depleted.
In individuals who are taking other drugs, have medical problems that are known to induce hyponatremia, or have conditions that promote the release of antidiuretic hormone, treatment with sulfonylureas may result in hyponatremia. Certain sulfonylureas have been linked to the syndrome of inappropriate antidiuretic hormone (SIADH) secretion, and these medications may enhance the peripheral (antidiuretic) action of ADH or increase ADH release. Patients with hyponatremia or those who are more likely to develop it, such as the elderly, those on diuretics, or those who are volume-depleted, should be treated with caution.
How to manage the interaction:
Treatment with sulfonylureas may cause hyponatremia (low sodium level), in patients who are on other medications or have medical conditions known to cause hyponatremia or increase release of antidiuretic hormone. Caution should be used when treating patients with hyponatremia or at greater risk of developing hyponatremia such as elderly patients, patients taking diuretics or those who are volume-depleted.
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