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  3. Siroglob 1mg Tablet

Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Sureshvarma D , MPharma
48 Hrs returnable
COD available

Online payment accepted

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Whats That

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Composition :

SIROLIMUS-1MG

Consume Type :

ORAL

Return Policy :

Not Returnable

Therapeutic Class

IMMUNOSUPPRESSANTS

Country of origin

India
Other Info - SI82600

Author Details

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FAQs

Siroglob 1mg Tablet contains Sirolimus is an immunosuppressant. It works by weakening your body's defence system (immune system) to help your body accept the new organ as if it were your own.

No, it is a prescribed drug given by a physician for preventing specific medical conditions. Taking it on your own can cause unwanted side effects.

Siroglob 1mg Tablet is safe if used in the dose and duration recommended by your doctor. Take it exactly as directed, and do not skip any dose. Follow your doctor's guidelines carefully and inform your doctor if any of the side effects disturb you.

Please do not stop using Siroglob 1mg Tablet without consulting your doctor on your own. Continue using Siroglob 1mg Tablet for as long as your doctor has prescribed it to treat your condition effectually. Do not be reluctant to speak with your doctor if you experience any difficulty while taking Siroglob 1mg Tablet.

Take the missed dose as soon as possible. However, skip the missed dose and return to your regular dosing schedule if it is time for the next dose.

Disclaimer

While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.
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Alcohol

Caution

It is advised to avoid alcohol intake since it may worsen the side effects.

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Pregnancy

Caution

Consult your doctor, and there is no substantial research yet on the use of Siroglob 1mg Tablet in pregnant women.

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Breast Feeding

Caution

Consult your doctor, and there is no substantial research yet on the use of Siroglob 1mg Tablet in breastfeeding/nursing mothers.

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Driving

Caution

Do not drive or operate machinery if you experience dizziness or drowsiness while using Siroglob 1mg Tablet. Siroglob 1mg Tablet can also sometimes cause dizziness/drowsiness; hence avoid driving in such situations. Seek medical attention if the symptoms persist longer.

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Liver

Caution

Please consult your doctor if you have any concerns regarding using Siroglob 1mg Tablet in patients with liver impairment. Your doctor will prescribe only if the benefits outweigh the risks.

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Kidney

Caution

Please consult your doctor if you have any concerns regarding using Siroglob 1mg Tablet in patients with kidney impairment. Your doctor will prescribe only if the benefits outweigh the risks.

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Children

Caution

There is limited information available on the use of Siroglob 1mg Tablet in children. Please consult your doctor.

About Siroglob 1mg Tablet

Siroglob 1mg Tablet belongs to a class of drugs called 'immunosuppressants' used to prevent organ rejection after a transplant. Organ rejection occurs when a patient's immune system recognizes the donor organ as foreign and tries to eliminate it.

Siroglob 1mg Tablet contains Sirolimus is an immunosuppressant. It weakens your body's defence system (immune system) to help your body accept the new organ as if it were your own. Thereby preventing organ rejection in transplanted patients and assisting the body in accepting the new organ.

Use Siroglob 1mg Tablet as prescribed by your doctor. You are advised to use Siroglob 1mg Tablet for as long as your doctor has prescribed it based on your medical condition. Some people may experience abdominal pain, diarrhoea, headache, fever, urinary tract infection, anaemia, nausea, arthralgia, pain, and oedema. Most of these side effects of Siroglob 1mg Tablet do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.

To treat your condition effectually, continue using Siroglob 1mg Tablet for as long as your doctor has prescribed it. Do not use Siroglob 1mg Tablet without a doctor's advice if you are allergic to Siroglob 1mg Tablet or other medicines. Consult your doctor before using Siroglob 1mg Tablet if you are pregnant or breastfeeding. Avoid alcohol consumption with Siroglob 1mg Tablet as it may increase the risk of severe adverse effects. Keep your doctor informed about your health condition and all the medicines you take before taking Siroglob 1mg Tablet to rule out any side effects.

Uses of Siroglob 1mg Tablet

Organ transplant rejection

Medicinal Benefits Mweb

Medicinal Benefits

Siroglob 1mg Tablet contains Sirolimus is an immunosuppressant. It weakens your body's defence system (immune system) to help your body accept the new organ as if it were your own. Thereby preventing organ rejection in transplanted patients and assisting the body in accepting the new organ.

Directions for Use

Swallow it as a whole with water; do not crush, break or chew it.

Side Effects of Siroglob 1mg Tablet

  • Peripheral oedema
  • Hypertriglyceridemia
  • Hypertension
  • Hypercholesterolemia
  • Creatinine increased
  • Abdominal pain
  • Diarrhoea
  • Headache
  • Fever
  • Urinary tract infection
  • Anaemia
  • Nausea
  • Arthralgia
  • Pain
  • Thrombocytopenia

Drug Warnings

Therapeutic drug monitoring is required for all patients receiving Siroglob 1mg Tablet. To treat your condition effectually, continue using Siroglob 1mg Tablet for as long as your doctor has prescribed it. Do not use Siroglob 1mg Tablet without a doctor's advice if you are allergic to Siroglob 1mg Tablet or other medicines. Consult your doctor before using the Siroglob 1mg Tablet if you are pregnant or breastfeeding. Avoid alcohol consumption with Siroglob 1mg Tablet as it may increase the risk of severe adverse effects. Do not use Siroglob 1mg Tablet in more than prescribed doses or longer duration as it may cause adverse effects. And also, keep your doctor informed about your health condition and all the medicines you take before taking Siroglob 1mg Tablet to rule out any side effects.

Drug-Drug Interactions

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Drug-Drug Interactions

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How does the drug interact with Siroglob 1mg Tablet:
Coadministration of Siroglob 1mg Tablet with Mifepristone can increase the levels of Siroglob 1mg Tablet in the blood, which can increase the risk or severity of side effects.

How to manage the interaction:
Taking Siroglob 1mg Tablet with Mifepristone is not recommended, they can be taken together if a doctor advises. However, contact a doctor if you experience any symptoms like back pain · difficulty falling asleep or staying asleep, fever, headache, joint pain, rash, stomach pain, constipation, or diarrhea. Do not stop taking any medications without consulting a doctor.
How does the drug interact with Siroglob 1mg Tablet:
Coadministration of Siroglob 1mg Tablet and Voriconazole can increase blood levels and side effects of Voriconazole.

How to manage the interaction:
Taking Voriconazole with Siroglob 1mg Tablet is generally avoided as it can result in an interaction, please consult a doctor before taking it. Contact a doctor if you experience nausea, fever, abdominal pain, or yellowing of the skin or eyes. Do not stop using any medication without consulting a doctor.
SirolimusBCG vaccine
Critical
How does the drug interact with Siroglob 1mg Tablet:
Coadministration of Siroglob 1mg Tablet with the BCG vaccine can make the vaccine less effective.

How to manage the interaction:
Taking Siroglob 1mg Tablet with the BCG vaccine is not recommended, they can be taken together if advised by your doctor. However, contact your doctor if you experience any symptoms. Do not stop taking any medications without consulting a doctor.
How does the drug interact with Siroglob 1mg Tablet:
Coadministration of Siroglob 1mg Tablet with posaconazole can lower the levels of Siroglob 1mg Tablet in the blood.

How to manage the interaction:
Although there is an interaction between posaconazole with Siroglob 1mg Tablet, they can be taken together if a doctor advises. However, if you experience any unusual symptoms contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Siroglob 1mg Tablet:
Co-administration of Cidofovir and Siroglob 1mg Tablet can increase the risk or severity of Kidney problems.

How to manage the interaction:
Taking Siroglob 1mg Tablet with Cidofovir is not recommended, but it can be taken together if prescribed by a doctor. However, if you experience nausea, vomiting, loss of hunger, increased or decreased urination, sudden weight gain or loss, fluid retention, swelling, shortness of breath, muscle cramps, tiredness, weakness, dizziness, confusion, or an irregular heart rhythm, consult a doctor. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Siroglob 1mg Tablet:
Coadministration of Tofacitinib with Siroglob 1mg Tablet may increase the risk or severity of developing infection.

How to manage the interaction:
Although there is a possible interaction between Siroglob 1mg Tablet and Tofacitinib, you can take these medicines together if prescribed by a doctor. However, consult the doctor immediately if you experience symptoms such as fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, blood in phlegm, weight loss, red or inflamed skin, body sores, and pain or burning during urination. Do not stop using any medications without a doctor's advice.
How does the drug interact with Siroglob 1mg Tablet:
Co-administration of Siroglob 1mg Tablet with Methotrexate can increase the risk or severity of kidney damage.

How to manage the interaction:
Although there is a possible interaction between Siroglob 1mg Tablet and methotrexate, you can take these medicines together if prescribed by a doctor. However, if you experience nausea, vomiting, a decrease in hunger, increased or decreased urine, weight gain or loss that occurs suddenly, fluid retention, swelling, difficulty breathing, muscle pain, fatigue, weakness, dizziness, confusion, and irregular heartbeat, consult a doctor. Do not discontinue any medications without a doctor's advice.
How does the drug interact with Siroglob 1mg Tablet:
Co-administration of Phenobarbital and Siroglob 1mg Tablet can reduce the effectiveness of Siroglob 1mg Tablet, which may make Siroglob 1mg Tablet less effective in treating the condition.

How to manage the interaction:
Although taking phenobarbital and Siroglob 1mg Tablet together can result in an interaction, it can be taken if a doctor has prescribed it. Do not stop using any medications without a doctor's advice.
SirolimusEnzalutamide
Severe
How does the drug interact with Siroglob 1mg Tablet:
Coadministration of Enzalutamide with Siroglob 1mg Tablet may decrease the blood levels of Siroglob 1mg Tablet, which may lead to reduced treatment outcomes.

How to manage the interaction:
Although taking Enzalutamide and Siroglob 1mg Tablet together can possibly result in an interaction, it can be taken if a doctor has prescribed it. Do not stop using any medication without consulting a doctor.
How does the drug interact with Siroglob 1mg Tablet:
Coadministration of Etodolac and Siroglob 1mg Tablet can increase the risk or severity of kidney problems.

How to manage the interaction:
Although taking Siroglob 1mg Tablet and Etodolac together can cause an interaction, it can be taken if a doctor has suggested it. However, consult a doctor if you experience nausea, vomiting, loss of appetite, increased or decreased urination, sudden weight gain or loss, fluid retention, swelling, shortness of breath, muscle cramps, tiredness, weakness, dizziness, confusion, or an irregular heart rhythm. Do not discontinue any medications without a doctor's advice.

Drug-Food Interactions

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SIROLIMUS-1MGGrapefruit and Grapefruit Juice
Moderate

Drug-Food Interactions

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SIROLIMUS-1MGGrapefruit and Grapefruit Juice
Moderate
Common Foods to Avoid:
Grapefruit Juice, Grapefruit

How to manage the interaction:
Taking Siroglob 1mg Tablet with Grapefruit and Grapefruit juice may increase the side effects of Siroglob 1mg Tablet. Avoid or limit consumption of Grapefruit and Grapefruit juice while taking Siroglob 1mg Tablet.

Drug-Diseases Interactions

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No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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Drug-Drug Interactions Checker List

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No

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