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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Sureshvarma D , MPharma
48 Hrs returnable
COD available

Online payment accepted

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Whats That

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Composition :

SIROLIMUS-1MG

Manufacturer/Marketer :

Zydus Healthcare Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

Therapeutic Class

IMMUNOSUPPRESSANTS

Country of origin

India

Manufacturer/Marketer address

Zydus Tower, Satellite Cross Roads,Ahmedabad – 380015 Gujarat, India.
Other Info - SIR0009

Author Details

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FAQs

Siromus Tablet contains Sirolimus is an immunosuppressant. It works by weakening your body's defence system (immune system) to help your body accept the new organ as if it were your own.

No, it is a prescribed drug given by a physician for preventing specific medical conditions. Taking it on your own can cause unwanted side effects.

Siromus Tablet is safe if used in the dose and duration recommended by your doctor. Take it exactly as directed, and do not skip any dose. Follow your doctor's guidelines carefully and inform your doctor if any of the side effects disturb you.

Please do not stop using Siromus Tablet without consulting your doctor on your own. Continue using Siromus Tablet for as long as your doctor has prescribed it to treat your condition effectually. Do not be reluctant to speak with your doctor if you experience any difficulty while taking Siromus Tablet.

Take the missed dose as soon as possible. However, skip the missed dose and return to your regular dosing schedule if it is time for the next dose.

Disclaimer

While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.
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Alcohol

Caution

It is advised to avoid alcohol intake since it may worsen the side effects.

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Pregnancy

Caution

Consult your doctor, and there is no substantial research yet on the use of Siromus Tablet in pregnant women.

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Breast Feeding

Caution

Consult your doctor, and there is no substantial research yet on the use of Siromus Tablet in breastfeeding/nursing mothers.

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Driving

Caution

Do not drive or operate machinery if you experience dizziness or drowsiness while using Siromus Tablet. Siromus Tablet can also sometimes cause dizziness/drowsiness; hence avoid driving in such situations. Seek medical attention if the symptoms persist longer.

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Liver

Caution

Please consult your doctor if you have any concerns regarding using Siromus Tablet in patients with liver impairment. Your doctor will prescribe only if the benefits outweigh the risks.

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Kidney

Caution

Please consult your doctor if you have any concerns regarding using Siromus Tablet in patients with kidney impairment. Your doctor will prescribe only if the benefits outweigh the risks.

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Children

Caution

There is limited information available on the use of Siromus Tablet in children. Please consult your doctor.

About Siromus Tablet

Siromus Tablet belongs to a class of drugs called 'immunosuppressants' used to prevent organ rejection after a transplant. Organ rejection occurs when a patient's immune system recognizes the donor organ as foreign and tries to eliminate it.

Siromus Tablet contains Sirolimus is an immunosuppressant. It weakens your body's defence system (immune system) to help your body accept the new organ as if it were your own. Thereby preventing organ rejection in transplanted patients and assisting the body in accepting the new organ.

Use Siromus Tablet as prescribed by your doctor. You are advised to use Siromus Tablet for as long as your doctor has prescribed it based on your medical condition. Some people may experience abdominal pain, diarrhoea, headache, fever, urinary tract infection, anaemia, nausea, arthralgia, pain, and oedema. Most of these side effects of Siromus Tablet do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.

To treat your condition effectually, continue using Siromus Tablet for as long as your doctor has prescribed it. Do not use Siromus Tablet without a doctor's advice if you are allergic to Siromus Tablet or other medicines. Consult your doctor before using Siromus Tablet if you are pregnant or breastfeeding. Avoid alcohol consumption with Siromus Tablet as it may increase the risk of severe adverse effects. Keep your doctor informed about your health condition and all the medicines you take before taking Siromus Tablet to rule out any side effects.

Uses of Siromus Tablet

Organ transplant rejection

Medicinal Benefits Mweb

Medicinal Benefits

Siromus Tablet contains Sirolimus is an immunosuppressant. It weakens your body's defence system (immune system) to help your body accept the new organ as if it were your own. Thereby preventing organ rejection in transplanted patients and assisting the body in accepting the new organ.

Directions for Use

Swallow it as a whole with water; do not crush, break or chew it.

Side Effects of Siromus Tablet

  • Peripheral oedema
  • Hypertriglyceridemia
  • Hypertension
  • Hypercholesterolemia
  • Creatinine increased
  • Abdominal pain
  • Diarrhoea
  • Headache
  • Fever
  • Urinary tract infection
  • Anaemia
  • Nausea
  • Arthralgia
  • Pain
  • Thrombocytopenia

Drug Warnings

Therapeutic drug monitoring is required for all patients receiving Siromus Tablet. To treat your condition effectually, continue using Siromus Tablet for as long as your doctor has prescribed it. Do not use Siromus Tablet without a doctor's advice if you are allergic to Siromus Tablet or other medicines. Consult your doctor before using the Siromus Tablet if you are pregnant or breastfeeding. Avoid alcohol consumption with Siromus Tablet as it may increase the risk of severe adverse effects. Do not use Siromus Tablet in more than prescribed doses or longer duration as it may cause adverse effects. And also, keep your doctor informed about your health condition and all the medicines you take before taking Siromus Tablet to rule out any side effects.

Drug-Drug Interactions

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Drug-Drug Interactions

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How does the drug interact with Siromus Tablet:
Coadministration of Siromus Tablet with posaconazole can lower the levels of Siromus Tablet in the blood.

How to manage the interaction:
Although there is an interaction between posaconazole with Siromus Tablet, they can be taken together if a doctor advises. However, if you experience any unusual symptoms contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Siromus Tablet:
Coadministration of Siromus Tablet with Mifepristone can increase the levels of Siromus Tablet in the blood, which can increase the risk or severity of side effects.

How to manage the interaction:
Taking Siromus Tablet with Mifepristone is not recommended, they can be taken together if a doctor advises. However, contact a doctor if you experience any symptoms like back pain · difficulty falling asleep or staying asleep, fever, headache, joint pain, rash, stomach pain, constipation, or diarrhea. Do not stop taking any medications without consulting a doctor.
SirolimusBCG vaccine
Critical
How does the drug interact with Siromus Tablet:
Coadministration of Siromus Tablet with the BCG vaccine can make the vaccine less effective.

How to manage the interaction:
Taking Siromus Tablet with the BCG vaccine is not recommended, they can be taken together if advised by your doctor. However, contact your doctor if you experience any symptoms. Do not stop taking any medications without consulting a doctor.
How does the drug interact with Siromus Tablet:
Coadministration of Siromus Tablet and Voriconazole can increase blood levels and side effects of Voriconazole.

How to manage the interaction:
Taking Voriconazole with Siromus Tablet is generally avoided as it can result in an interaction, please consult a doctor before taking it. Contact a doctor if you experience nausea, fever, abdominal pain, or yellowing of the skin or eyes. Do not stop using any medication without consulting a doctor.
How does the drug interact with Siromus Tablet:
Co-administration of Cidofovir and Siromus Tablet can increase the risk or severity of Kidney problems.

How to manage the interaction:
Taking Siromus Tablet with Cidofovir is not recommended, but it can be taken together if prescribed by a doctor. However, if you experience nausea, vomiting, loss of hunger, increased or decreased urination, sudden weight gain or loss, fluid retention, swelling, shortness of breath, muscle cramps, tiredness, weakness, dizziness, confusion, or an irregular heart rhythm, consult a doctor. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Siromus Tablet:
Coadministration of Siromus Tablet with Clotrimazole may significantly increase the blood levels of Siromus Tablet. This may increase the risk of serious side effects such as kidney problems, hyperkalemia (high potassium levels in the blood), and high blood pressure.

How to manage the interaction:
Although taking Clotrimazole with Siromus Tablet may possibly result in an interaction, they can be taken together if prescribed by a doctor. However, if you experience fever, chills, diarrhoea, sore throat, muscle aches, shortness of breath, weight loss, red or inflamed skin, body sores, and pain or burning during urination, consult a doctor immediately. Do not discontinue any medication without consulting a doctor.
How does the drug interact with Siromus Tablet:
Coadministration of Siromus Tablet with Streptomycin can increase the risk or severity of kidney problems.

How to manage the interaction:
Taking Streptomycin with Siromus Tablet can possibly result in an interaction, it can be taken if prescribed by your doctor. If you experience nausea, vomiting, loss of appetite, increased or decreased urination, sudden weight gain or weight loss, fluid retention, swelling, shortness of breath, bone pain, muscle cramps, tiredness, weakness, dizziness, confusion, irregular heart rhythm. Do not discontinue any medication without consulting a doctor.
How does the drug interact with Siromus Tablet:
Co-administration of Siromus Tablet and Zoledronic acid can increase the risk or severity of kidney problems.

How to manage the interaction:
Taking Siromus Tablet and Zoledronic acid together can lead to an interaction, but it can be taken if a doctor advises. However, if you experience any symptoms like nausea, vomiting, loss of appetite, increased or decreased urination, sudden weight gain or weight loss, fluid retention, swelling, shortness of breath, muscle cramps, tiredness, weakness, dizziness, confusion, and irregular heart rhythm, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Siromus Tablet:
Co-administration of Diclofenac with Siromus Tablet may increase the risk or severity of kidney problems.

How to manage the interaction:
Co-administration of Diclofenac and Siromus Tablet can lead to an interaction, but it can be taken if advised by a doctor. However, consult a doctor if you experience any symptoms like nausea, vomiting, loss of appetite, increased or decreased urination, sudden weight gain or weight loss, fluid retention, swelling, shortness of breath, muscle cramps, tiredness, weakness, dizziness, confusion, and irregular heart rhythm. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Siromus Tablet:
Co-administration of Siromus Tablet and Ketorolac may increase the risk or severity of kidney issues.

How to manage the interaction:
Although taking Ketorolac and Siromus Tablet together can possibly result in an interaction, it can be taken if a doctor has prescribed it. However, if you experience symptoms like nausea, vomiting, loss of appetite, increased or decreased urination, sudden weight gain or loss, fluid retention, swelling, shortness of breath, cramps in your muscles, fatigue, weakness, dizziness, confusion, and irregular heartbeat, consult a doctor. Do not stop using any medication without consulting your doctor.

Drug-Food Interactions

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SIROLIMUS-1MGGrapefruit and Grapefruit Juice
Moderate

Drug-Food Interactions

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SIROLIMUS-1MGGrapefruit and Grapefruit Juice
Moderate
Common Foods to Avoid:
Grapefruit Juice, Grapefruit

How to manage the interaction:
Taking Siromus Tablet with Grapefruit and Grapefruit juice may increase the side effects of Siromus Tablet. Avoid or limit consumption of Grapefruit and Grapefruit juice while taking Siromus Tablet.

Drug-Diseases Interactions

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No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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Drug-Drug Interactions Checker List

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No

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