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  3. Tobamist Respules 5X5 ml

Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
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About Tobamist Respules 5X5 ml

Tobamist Respules 5X5 ml belongs to the class of aminoglycoside antibiotics. Tobamist Respules 5X5 ml is used to treat chest infections caused by the bacteria Pseudomonas aeruginosa in cystic fibrosis patients aged six years and older. Pseudomonas aeruginosa is a type of bacteria that can cause lung or chest infections, especially in people who already have a lung disease (cystic fibrosis) or an issue with their immune system.

Tobamist Respules 5X5 ml contains Tobramycin, an aminoglycoside antibiotic that fights the infection in your lungs by interfering with protein synthesis in Pseudomonas bacterial cell and helps you breathe better.

Use the Tobamist Respules 5X5 ml as prescribed by your doctor. Sometimes, you may experience certain common side effects, such as runny or stuffy nose, sneezing, voice alteration (hoarseness), discolouration of the substance you cough up (sputum), worsening of lung function test results, feeling unwell, muscle pain and voice alteration with sore throat and difficulty swallowing (laryngitis). Most of these side effects do not require medical attention and resolve gradually over time. However, you are advised to talk to your doctor if you experience these side effects persistently.

Do not use Tobamist Respules 5X5 ml if you are allergic to any of its components or other aminoglycoside antibiotics. Do not use the Tobamist Respules 5X5 ml without consulting your doctor if you are pregnant or breastfeeding. Tell your doctor before prescribing Tobamist Respules 5X5 ml if you have hearing problems, kidney problems, unusual difficulty breathing with wheezing or coughing, chest tightness, blood in the sputum, muscle weakness, and Parkinson's disease. Tobamist Respules 5X5 ml is not recommended to be used in children under the age of six.

Uses of Tobamist Respules 5X5 ml

Chest infections (Pseudomonas aeruginosa infection)

Therapeutic Class

[ANTIBIOTICS]

Medicinal Benefits

Key Benefits

Tobamist Respules 5X5 ml contains Tobramycin, an aminoglycoside antibiotic that fights pulmonary infection by interfering with protein synthesis in Pseudomonas bacterial cells and allows you to breathe easier.

Directions for Use

Check the label for directions before using the Tobamist Respules 5X5 ml. It is for inhalation only. Do not swallow the respules. Use it in the dose and for the duration advised by your doctor.

Side Effects of Tobamist Respules 5X5 ml

  • Runny or stuffy nose, sneezing
  • Voice alteration (hoarseness)
  • Discolouration of the substance you cough up (sputum)
  • Worsening of lung function test results
  • Generally feeling unwell
  • Muscle pain
  • Voice alteration with a sore throat
  • Difficulty swallowing (laryngitis)
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Alcohol

Safe if prescribed

It is unknown if alcohol affects Tobamist Respules 5X5 ml. However, it is advisable to limit or avoid alcohol as a precautionary measure.

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Pregnancy

Consult your doctor

Tobamist Respules 5X5 ml may not be recommended to be used in pregnancy. If you are pregnant, please consult your doctor. Your doctor will prescribe only if the benefits outweigh the risks.

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Breast Feeding

Consult your doctor

Consult your doctor as there is no substantial research yet on using Tobamist Respules 5X5 ml in breastfeeding/nursing mothers.

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Driving

Safe if prescribed

Tobamist Respules 5X5 ml may not affect your ability to drive, use, or operate machines.

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Liver

Consult your doctor

Limited information about the usage of Tobamist Respules 5X5 ml in patients with liver disease is available. Please consult your physician. Your doctor will weigh the benefits and potential risks before prescribing Tobamist Respules 5X5 ml.

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Kidney

Consult your doctor

Limited information about the usage of Tobamist Respules 5X5 ml in patients with kidney disease is available. Please consult your physician. Your doctor will weigh the benefits and potential risks before prescribing Tobamist Respules 5X5 ml.

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Children

Safe if prescribed

Children and adolescents aged six and up are eligible to use Tobamist Respules 5X5 ml. Tobamist Respules 5X5 ml should not be given to children under the age of six.

Drug-Diseases Interactions

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No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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Drug Warnings

Do not use Tobamist Respules 5X5 ml if you are allergic to any of the components or other aminoglycoside antibiotics (neomycin, paromomycin, kanamycin). Do not use the Tobamist Respules 5X5 ml without consulting your doctor if you are pregnant or breastfeeding. Tell your doctor before prescribing Tobamist Respules 5X5 ml if you have hearing problems, kidney problems, unusual difficulty breathing with wheezing or coughing, chest tightness, blood in the sputum, muscle weakness, and Parkinson's disease. Children and adolescents aged six and up are eligible to use Tobamist Respules 5X5 ml. Tobamist Respules 5X5 ml should not be given to children under the age of six. Before taking the Tobamist Respules 5X5 ml, notify your doctor about your medical history and other medications you are now taking to rule out any potential adverse effects or interactions.

Drug-Drug Interactions

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TobramycinDoxacurium chloride
Severe

Drug-Drug Interactions

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How does the drug interact with Tobamist Respules 5X5 ml:
Coadministration of cidofovir with Tobamist Respules 5X5 ml can cause kidney problems.

How to manage the interaction:
Taking Tobamist Respules 5X5 ml with Cidofovir is not recommended, but can be taken if prescribed by a doctor. However, if you experience nausea, vomiting, loss of appetite, increased or decreased urination, sudden weight gain or weight loss, swelling, shortness of breath, bone pain, muscle cramps, tiredness, weakness, dizziness, confusion, and irregular heart rhythm contact your doctor immediately. Do not stop using any medications without consulting a doctor.
TobramycinDoxacurium chloride
Severe
How does the drug interact with Tobamist Respules 5X5 ml:
Taking Tobamist Respules 5X5 ml with doxacurium chloride can increase the risk of respiratory depression(hypoventilation).

How to manage the interaction:
Although there is a possible interaction between Tobamist Respules 5X5 ml and Doxacurium chloride, you can take these medicines together if prescribed by your doctor. Do not stop using any medications without a doctor's advice.
How does the drug interact with Tobamist Respules 5X5 ml:
Taking tacrolimus with Tobamist Respules 5X5 ml may increase risk of kidney problems.

How to manage the interaction:
Although taking tacrolimus and Tobamist Respules 5X5 ml together can possibly result in an interaction, it can be taken if your doctor has prescribed it. However, consult the doctor immediately if you experience symptoms such as nausea, vomiting, loss of hunger, increased or decreased urination, sudden weight gain or weight loss, fluid retention, swelling, shortness of breath, muscle cramps, tiredness, weakness, dizziness, confusion, and irregular heart rhythm. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Tobamist Respules 5X5 ml:
Taking Tobamist Respules 5X5 ml with succinylcholine can increase the risk of respiratory depression(hypoventilation).

How to manage the interaction:
There may be a possibility of interaction between Suxamethonium and Tobamist Respules 5X5 ml, but it can be taken if prescribed by a doctor. Do not discontinue any medications without first consulting your doctor.
TobramycinFoscarnet
Severe
How does the drug interact with Tobamist Respules 5X5 ml:
Combining Tobamist Respules 5X5 ml with Foscarnet can increase the risk of kidney problems.

How to manage the interaction:
There may be a possibility of interaction between Tobamist Respules 5X5 ml and foscarnet, but it can be taken if prescribed by a doctor. However, if you experience nausea, swelling, sudden weight gain or weight loss, severe pain in your upper stomach spreading to your back, seizures, pounding heart beats, dizziness or chest pain contact your doctor immediately. Do not stop using any medications without first talking to your doctor.
How does the drug interact with Tobamist Respules 5X5 ml:
Coadministration of Tobamist Respules 5X5 ml with Tenofovir disoproxil can increase the risk of kidney problems.

How to manage the interaction:
Taking Tenofovir disoproxil with Tobamist Respules 5X5 ml together can possibly result in an interaction, but it can be taken if your doctor has advised it. However, if you experience nausea, vomiting, loss of appetite, increased or decreased urination, sudden weight gain or weight loss, swelling, shortness of breath, bone pain, muscle cramps, tiredness, weakness, dizziness, confusion, and irregular heart rhythm, contact your doctor immediately. Do not discontinue any medications without consulting your doctor.
How does the drug interact with Tobamist Respules 5X5 ml:
Coadministration of Tobamist Respules 5X5 ml with Colistin can increase the blood levels and risk of Colistin side effects.

How to manage the interaction:
Although there is a possible interaction between Colistin and Tobamist Respules 5X5 ml, you can take these medicines together if prescribed by your doctor. However, if you experience, shortness of breath, muscle pain, dizziness, or palpitations, contact your doctor immediately. Do not stop using any medications without a doctor's advice.
How does the drug interact with Tobamist Respules 5X5 ml:
Taking tenofovir alafenamide with Tobamist Respules 5X5 ml can increase the risk of kidney problems.

How to manage the interaction:
Although taking Tenofovir alafenamide and Tobamist Respules 5X5 ml together can evidently cause an interaction, it can be taken if your doctor has suggested it. However, if you experience nausea, vomiting, loss of appetite, increased or decreased urination, sudden weight gain or weight loss, fluid retention, swelling, shortness of breath, bone pain, muscle cramps, tiredness, weakness, dizziness, confusion, and irregular heart rhythm contact your doctor immediately. Do not stop using any medications without a doctor's advice.
How does the drug interact with Tobamist Respules 5X5 ml:
Using pancuronium with Tobamist Respules 5X5 ml can increase the risk of respiratory depression(hypoventilation).

How to manage the interaction:
Although taking Pancuronium and Tobamist Respules 5X5 ml together can evidently cause an interaction, it can be taken if your doctor has suggested it. Do not stop using any medications without first talking to your doctor.
How does the drug interact with Tobamist Respules 5X5 ml:
Taking Tobamist Respules 5X5 ml with Polymyxin B can increase the risk of side effects.

How to manage the interaction:
Although there is an interaction between Tobamist Respules 5X5 ml and Polymyxin b, you can take these medicines together if prescribed by a doctor. However, if you experience hearing loss, ringing in the ears, difficulty breathing, nausea, vomiting, loss of appetite, increased or decreased urination, sudden weight gain or weight loss, swelling, muscle cramps, tiredness, weakness, dizziness, confusion, and irregular heart rhythm contact a doctor immediately. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Drug-Drug Interactions Checker List

  • SALBUTAMOL
  • FUROSEMIDE
  • ETHACRYNIC ACID
  • MANNITOL

Habit Forming

No

Diet & Lifestyle Advise

  • It would be best to take probiotics after taking the full course of Tobamist Respules 5X5 ml to restore some healthy bacteria in the intestine that may have been killed. Taking probiotics after antibiotic treatment can reduce the risk of antibiotic-associated diarrhoea. Certain fermented foods like yoghurt, cheese, sauerkraut and kimchi can help restore the intestine's good bacteria.
  • Include more fibre-enriched food in your diet, as it can be easily digested by gut bacteria which helps stimulate their growth. Thus fibre foods may help restore healthy gut bacteria after taking a course of antibiotics. Whole grains, like whole-grain bread, and brown rice, should be included in your diet.
  • Avoid taking too many calcium-enriched foods and drinks as it might affect the working of Tobamist Respules 5X5 ml.
  • Avoid intake of alcoholic beverages with Tobamist Respules 5X5 ml as it can make you dehydrated and affect your sleep. This can make it harder for your body to aid the Tobamist Respules 5X5 ml in fighting off infections.

FAQs

Tobamist Respules 5X5 ml contains Tobramycin, an aminoglycoside antibiotic that fights pulmonary infection by interfering with protein synthesis in Pseudomonas bacterial cells and allows you to breathe easier.

Please do not stop using Tobamist Respules 5X5 ml until the course prescribed by your doctor has been completed. If you stop taking Tobamist Respules 5X5 ml too soon, your symptoms may recur.

Voice alteration (hoarseness) is the most common side effect of Tobamist Respules 5X5 ml. If you experience any major changes, immediately consult your doctor.

Tobamist Respules 5X5 ml is recommended not to use it for more than the prescribed duration. Please reach out to your doctor if your symptoms do not improve or if it becomes worse.

Tobamist Respules 5X5 ml is only used to treat chest infections caused by the bacteria Pseudomonas aeruginosa in cystic fibrosis patients.

Country of origin

India

Manufacturer/Marketer address

Cipla House, Peninsula Business Park, Ganpatrao Kadam Marg, Lower Parel, Mumbai-400013
Other Info - TOB0011

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