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  1. Home
  2. OTC

  3. Powergesic Plus Gel 30 gm

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About Powergesic Plus Gel

Powergesic Plus Gel is a topical analgesic (pain killer) primarily used to relieve acute musculoskeletal pain and pain of osteoarthritis of joints. It reduces pain, swelling, and joint stiffness, thereby improving your ability to move and flex the joint.

Powergesic Plus Gel contains Diclofenac and Methyl salicylate (as a pain killer), Linseed oil (as an anti-inflammatory), and Menthol (as a cooling agent). Powergesic Plus Gel works by first cooling the skin and then warming it up, which interferes with the pain signal transmission through nerves. Together Powergesic Plus Gel works by blocking the release of chemical messengers that causes pain and inflammation with redness and swelling.

Powergesic Plus Gel should only be used if advised by your doctor. Powergesic Plus Gel should be used for skin only, and accidentally if it gets into your eye, mouth, or nose, rinse with water. Powergesic Plus Gel should be applied to the affected area with a piece of clean cotton wool or gauze swab. Powergesic Plus Gel should not be applied more than the recommended dose to avoid unpleasant side effects. Some common side effects of Powergesic Plus Gel are burning, itching, redness, stinging, and dryness on your skin in the place where Powergesic Plus Gel is applied. These side effects are usually mild and short-lived. However, if the side effects are persistent, reach out to your doctor.

Powergesic Plus Gel is contraindicated in children below two years of age. Besides this, caution must be exercised when older children (2-12 years) are treated. Children affected with viral flu, chickenpox, or viral fever should avoid using Powergesic Plus Gel as it contains methyl salicylate may induce Reyes Syndrome (swelling in the liver and brain).

Uses of Powergesic Plus Gel

Musculoskeletal pain, Joint pain of arthritis

Key Benefits

Powergesic Plus Gel contains Diclofenac and Methyl salicylate (as a pain killer), Linseed oil (as anti-inflammatory), and Menthol (as cooling agent). Powergesic Plus Gel works by first cooling the skin and then warming it up that interferes with the pain signal transmission through nerves. Together Powergesic Plus Gel works by blocking the release of chemical messengers that causes pain and inflammation with redness and swelling.

Directions for Use

Powergesic Plus Gel is for use on the skin surface (topical use) only. Do not apply to open wounds, external heat, or occlusive dressings to the treated joints. Avoid contact with eyes and mucous membranes. Cream/Ointment/Gel: It should be applied to the affected area with a piece of clean cotton wool or gauze swab. Before applying, wash your hands with soap and water and then gently rub it on the affected areas. Avoid taking a shower for at least 1 hour after the application.Spray: Spray it on the affected areas of the skin and gently rub it into the skin.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Powergesic Plus Gel

  • Skin irritation
  • Contact dermatitis
  • Rash
  • Itching
  • Redness
  • Swelling
  • Burning or stinging sensation

Drug Warnings

Before using Powergesic Plus Gel, tell your doctor if you are allergic to Powergesic Plus Gel other pain killers (like ibuprofen, naproxen, celecoxib) or if you have any other allergies. Use of Powergesic Plus Gel is contraindicated in the people who have asthma, liver disease, kidney disease, stomach/intestine problems (bleeding, ulcers, Crohn's disease), cardiovascular diseases (heart attack, high blood pressure, stroke), swelling (oedema, fluid retention), blood disorders (such as anaemia), bleeding/clotting problems. Powergesic Plus Gel should not be given to children less than 2 years of age. The use of Powergesic Plus Gel should be done with caution in the elderly as they have a high risk of kidney damage and gastrointestinal bleeding.

Drug Interactions

Drug-Drug Interaction: Powergesic Plus Gel may interact with ACE inhibitors (captopril, lisinopril), angiotensin II receptor blockers (losartan, valsartan), cidofovir, corticosteroids (dexamethasone, prednisone), lithium, methotrexate, diuretics (furosemide). Powergesic Plus Gel may increase the risk of bleeding when used with other drugs that also may cause bleeding.

Drug-Food Interaction: No interactions found.

Drug-Disease Interaction: No interactions found.

Drug-Drug Interactions Checker List

  • CAPTOPRIL
  • LISINOPRIL
  • LOSARTAN
  • VALSARTAN
  • CIDOFOVIR
  • DEXAMETHASONE
  • PREDNISONE
  • LITHIUM
  • METHOTREXATE
  • FUROSEMIDE

Habit Forming

No

Special Advise

Caution should be exercised, it is advisable to consult a doctor before using it. “Nonsteroidal anti-inflammatory drugs (NSAIDs) cause an increased risk of serious cardiovascular thrombotic events, including myocardial infarction and stroke.”

Disease/Condition Glossary

Osteoarthritis is a long term musculoskeletal joint disorder that causes damage to the cartilage and surrounding tissues characterized by pain, swelling, stiffness, and loss of function. The joint disorder becomes common with ageing and wear and tear of joints. Pain, swelling, bony overgrowth, and stiffness can be observed that follows inactivity and disappears within 30 minutes when the joint is moved. The diagnosis of osteoarthritis is based on symptoms and X-rays of the affected joints. Its treatment includes exercises, an analgesic that reduce pain and improve function, and finally joint replacement or other surgery like total knee replacement.

Consult Doctor

About Powergesic Plus Gel

Powergesic Plus Gel is a topical analgesic (pain killer) primarily used to relieve acute musculoskeletal pain and pain of osteoarthritis of joints. It reduces pain, swelling, and joint stiffness, thereby improving your ability to move and flex the joint.

Powergesic Plus Gel contains Diclofenac and Methyl salicylate (as a pain killer), Linseed oil (as an anti-inflammatory), and Menthol (as a cooling agent). Powergesic Plus Gel works by first cooling the skin and then warming it up, which interferes with the pain signal transmission through nerves. Together Powergesic Plus Gel works by blocking the release of chemical messengers that causes pain and inflammation with redness and swelling.

Powergesic Plus Gel should only be used if advised by your doctor. Powergesic Plus Gel should be used for skin only, and accidentally if it gets into your eye, mouth, or nose, rinse with water. Powergesic Plus Gel should be applied to the affected area with a piece of clean cotton wool or gauze swab. Powergesic Plus Gel should not be applied more than the recommended dose to avoid unpleasant side effects. Some common side effects of Powergesic Plus Gel are burning, itching, redness, stinging, and dryness on your skin in the place where Powergesic Plus Gel is applied. These side effects are usually mild and short-lived. However, if the side effects are persistent, reach out to your doctor.

Powergesic Plus Gel is contraindicated in children below two years of age. Besides this, caution must be exercised when older children (2-12 years) are treated. Children affected with viral flu, chickenpox, or viral fever should avoid using Powergesic Plus Gel as it contains methyl salicylate may induce Reyes Syndrome (swelling in the liver and brain).

Powergesic Plus Gel 30 gm, Pack of 1 GEL
Powergesic Plus Gel 30 gm, Pack of 1 GEL
Non returnable*
Know More
COD available

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Composition :

DICLOFENAC-1%W/W + LINSEED-3%W/W + MENTHOL-5%W/W + METHYL SALICYLATE-10%W/W

Manufacturer/Marketer :

Jenburkt Pharmaceuticals Ltd

Consume Type :

TOPICAL

Return Policy :

Not Returnable

Expires on or after :

Country of origin

INDIA

Manufacturer/Marketer address

Nirmala Apartments,93, Jayprakash Road, Andheri (West),Mumbai - 400 058. India.
Other Info - POW0002

FAQs

Sometimes drugs are not safe when you use them with certain other drugs and food. Taking them together can cause unpleasant side effects. Be sure to talk to your doctor about all the drugs you take.

Store in a dry and dark place at a temperature not exceeding 30°C. Do not freeze.

You should avoid the use of Powergesic Plus Gel if you have had any recent bypass heart surgery, heart attack, stroke, gastrointestinal bleeding (bloody stool), inflammation or ulcer of stomach/intestine. The elderly (more than 65 years of age) are at greater risk of having gastrointestinal bleeding so they should use Powergesic Plus Gel with caution.

No, Powergesic Plus Gel should be only used by the children who are more than 2 years of age. Powergesic Plus Gel is contraindicated in infants below 2 years of age.

No, use of Powergesic Plus Gel is contraindicated on the broken or cut wound skin. It should be only applied topically on the uppermost skin surfaces (epidermis). It should not be applied in the nostrils, vagina, or anus.

Disclaimer

While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.

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Alcohol

Caution

It is best to avoid alcohol while using the medication as its use with Powergesic Plus Gel might increase the chance of gastrointestinal bleeding.

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Pregnancy

Safe if prescribed

It is advisable to consult a doctor before using it.

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Breast Feeding

Safe if prescribed

Safety for use of Powergesic Plus Gel in lactation is not known, hence its benefit should be weighed against the possible risks to the mother and child.

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Driving

Safe if prescribed

Powergesic Plus Gel has no or negligible influence on the ability to drive or use machines.

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Liver

Safe if prescribed

Powergesic Plus Gel does not have any reported interaction. However, in severe liver diseases, the lowest effective dose should be used for the shortest duration possible.

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Kidney

Caution

No information is available on the efficacy and safety of Powergesic Plus Gel in patients with advanced kidney disease. Hence, treatment with Powergesic Plus Gel is not recommended in patients with advanced kidney disease. If Powergesic Plus Gel is used in this case then, close monitoring of the patient's kidney function is advisable.

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Children

Caution

Powergesic Plus Gel is contraindicated in infants below 2 years of age. Please consult your doctor for advice before using Powergesic Plus Gel.

Product Substitutes

Author Details

Bayyarapu Mahesh KumarDoctor badge

Written By

Bayyarapu Mahesh Kumar

M Pharmacy

Hari Kumar

Reviewed By

Hari Kumar

MBBS

Last Updated

Jul 8, 2025 | 9:29 AM IST

Doctor imageWe provide you with authentic, trustworthy and relevant information

Reference

  1. https://www.medicines.org.uk/emc/product/10950/smpc#
  2. https://ciplamed.com/printpdf/42573
  3. https://www.webmd.com/drugs/2/drug-174535-1065/diclofenac-methyl-salicylate-menthol-topical/diclofenac-1-topical/details

Uses of Powergesic Plus Gel

Musculoskeletal pain, Joint pain of arthritis

Key Benefits

Powergesic Plus Gel contains Diclofenac and Methyl salicylate (as a pain killer), Linseed oil (as anti-inflammatory), and Menthol (as cooling agent). Powergesic Plus Gel works by first cooling the skin and then warming it up that interferes with the pain signal transmission through nerves. Together Powergesic Plus Gel works by blocking the release of chemical messengers that causes pain and inflammation with redness and swelling.

Directions for Use

Powergesic Plus Gel is for use on the skin surface (topical use) only. Do not apply to open wounds, external heat, or occlusive dressings to the treated joints. Avoid contact with eyes and mucous membranes. Cream/Ointment/Gel: It should be applied to the affected area with a piece of clean cotton wool or gauze swab. Before applying, wash your hands with soap and water and then gently rub it on the affected areas. Avoid taking a shower for at least 1 hour after the application.Spray: Spray it on the affected areas of the skin and gently rub it into the skin.

Storage

Store in a cool and dry place away from sunlight

Drug Warnings

Before using Powergesic Plus Gel, tell your doctor if you are allergic to Powergesic Plus Gel other pain killers (like ibuprofen, naproxen, celecoxib) or if you have any other allergies. Use of Powergesic Plus Gel is contraindicated in the people who have asthma, liver disease, kidney disease, stomach/intestine problems (bleeding, ulcers, Crohn's disease), cardiovascular diseases (heart attack, high blood pressure, stroke), swelling (oedema, fluid retention), blood disorders (such as anaemia), bleeding/clotting problems. Powergesic Plus Gel should not be given to children less than 2 years of age. The use of Powergesic Plus Gel should be done with caution in the elderly as they have a high risk of kidney damage and gastrointestinal bleeding.

Therapeutic Class

ANALGESICS

Drug-Drug Interactions Checker List

  • CAPTOPRIL
  • LISINOPRIL
  • LOSARTAN
  • VALSARTAN
  • CIDOFOVIR
  • DEXAMETHASONE
  • PREDNISONE
  • LITHIUM
  • METHOTREXATE
  • FUROSEMIDE

Habit Forming

No

Special Advise

Caution should be exercised, it is advisable to consult a doctor before using it. “Nonsteroidal anti-inflammatory drugs (NSAIDs) cause an increased risk of serious cardiovascular thrombotic events, including myocardial infarction and stroke.”

Disease/Condition Glossary

Osteoarthritis is a long term musculoskeletal joint disorder that causes damage to the cartilage and surrounding tissues characterized by pain, swelling, stiffness, and loss of function. The joint disorder becomes common with ageing and wear and tear of joints. Pain, swelling, bony overgrowth, and stiffness can be observed that follows inactivity and disappears within 30 minutes when the joint is moved. The diagnosis of osteoarthritis is based on symptoms and X-rays of the affected joints. Its treatment includes exercises, an analgesic that reduce pain and improve function, and finally joint replacement or other surgery like total knee replacement.

Powergesic Plus Gel Substitute

Substitutes safety advice

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