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MENADIONE

About

MENADIONE is a vitamin supplement used to treat nutritional deficiencies. It is primarily used in the treatment of Vitamin K deficiency. Vitamin K is one of the important vitamins that help blood clotting and bone metabolism. Due to its coagulant properties, MENADIONE is also used in the prevention of anti-coagulant-induced prothrombin deficiency (increased risk of bleeding due to deficiency of prothrombin).

MENADIONE contains Menadione (Vitamin K3) which is a Vitamin K analogue. It works by helping the body make blood clotting factors such as Factor II, VII, IX, X in the liver, and anticoagulant proteins that prevent bleeding.

MENADIONE may cause certain side effects such as facial flushing, hemolysis, sweating, altered taste and injection site reactions. These side effects do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor immediately. MENADIONE is a parenteral medicine. It will be administered by a trained healthcare professional. Hence, do not administer by yourself. The dose of the medicine will be decided by your doctor depending on your condition.

MENADIONE should be avoided if allergic to it or any other components present in it. Keep your doctor informed about your complete health condition including the medications you take and medical history to rule out any side effects/interactions. Before administration, inform your doctor if you have G6PD deficiency (a genetic condition that causes the breakdown of red blood cells prematurely), as this medicine is contraindicated in those patients. Also inform your doctor if you have liver or kidney disease, if you are pregnant, planning to become pregnant or breastfeeding before receiving MENADIONE. 

Uses of MENADIONE

Vitamin K deficiency, Hypoprothrombinemia

Medicinal Benefits

MENADIONE contains Menadione (Vitamin K3) which is a Vitamin K analogue. It works by helping the body make blood clotting factors such as Factor II, VII, IX, X in the liver, and anticoagulant proteins that prevent bleeding.

Directions for Use

MENADIONE will be administered by a trained healthcare professional. Hence, do not self-administer.

Storage

Store in a cool and dry place away from sunlight

Side Effects of MENADIONE

  • Facial flushing
  • Sweating
  • Injection site reactions
  • Hemolysis
  • Altered taste

In-Depth Precautions and Warning

Drug Warnings

MENADIONE should be avoided if you are allergic to any components. Inform your doctor if you have a cholestatic disease, artificial heart valve, seizures, liver or kidney problems. Consult your doctor if you are pregnant or breastfeeding. MENADIONE is contraindicated in neonates and G6PD deficiency patients as it can cause serious side effects. Keep your doctor informed about your complete health condition including the current medications and medical history to rule out any side effects/interactions.

Drug Interactions

Drug-Drug Interactions: MENADIONE may interact with prothrombin-depressing anti-coagulants.

Drug-Food Interactions: No interactions found/established.

Drug-Disease Interactions: Inform your doctor if you have a cholestatic disease (impairment in bile formation/flow), artificial heart valve, G6PD deficiency, or liver problems.

Drug-Drug Interactions Checker List:

Safety Advice

  • Safety Warning

    Alcohol

    consult your doctor

    It is not known if alcohol interacts with MENADIONE. Please consult your doctor if you have any concerns.

  • Safety Warning

    Pregnancy

    caution

    If you are pregnant or planning pregnancy, inform your doctor before receiving MENADIONE. Your doctor may prescribe this medicine if the benefits outweigh the risks.

  • Safety Warning

    Breast Feeding

    caution

    If you are breastfeeding, inform your doctor before receiving MENADIONE. Your doctor may prescribe this medicine if the benefits outweigh the risks.

  • Safety Warning

    Driving

    consult your doctor

    MENADIONE generally does not affect your ability to drive. However, drive or operate machinery only if you are alert.

  • Safety Warning

    Liver

    caution

    If you have a pre-existing or a history of liver disease, inform your doctor before receiving MENADIONE.

  • Safety Warning

    Kidney

    caution

    If you have a pre-existing or a history of kidney disease, inform your doctor before receiving MENADIONE.

  • Safety Warning

    Children

    consult your doctor

    Vitamin K injections are given to newborn babies to prevent a dangerous condition known as haemorrhagic disease of the newborn (HDN). Consult your doctor for more information.

Habit Forming

No

Diet & Lifestyle Advise

  • Eat a balanced diet rich in vegetables and whole fruits.
  • Include green leafy vegetables, soybean and canola oil, and fortified meal replacement shakes.
  • Avoid smoking and alcohol consumption.
  • Exercising regularly helps in improving overall health. 
  • Rest well, and get plenty of sleep.
  • Meditation and yoga can help lower stress.
  • Avoid processed and fried food. 

Special Advise

 

Patients Concern

Disease/Condition Glossary

Vitamin K deficiency: It is caused by decreased production of vitamin K in the body and insufficient dietary intake, inadequate absorption, and decreased storage of vitamin K. Symptoms of vitamin K deficiency include easy bruising, nose bleeds, and bleeding caused by the inability to form clots.

Hypoprothrombinemia: It is characterized by a deficiency of the blood-clotting substance called prothrombin, which leads to prolonged bleeding. This condition is usually associated with vitamin K deficiency. Symptoms include easy bruising, abnormal bleeding, heavy bleeding, and nose bleeds.

FAQs

MENADIONE works by helping the body make blood clotting factors such as Factor II, VII, IX, X in the liver, and anticoagulant proteins that prevent bleeding.

MENADIONE may cause cyanosis, a condition characterized by bluish discolouration of the skin, lips, nails, or around the eyes. Consult your doctor if you have any concerns.

Available Medicines for

MENADIONE

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