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  3. BD-Zadine 100 Injection 1's

Written By Santoshini Reddy G , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
48 Hrs returnable
COD available

Online payment accepted

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Whats That

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Composition :

AZACITIDINE-100MG

Consume Type :

PARENTERAL

Return Policy :

Not Returnable

Therapeutic Class

CHEMOTHERAPY

Country of origin

India

Manufacturer/Marketer address

407-408, Sharda Chambers, New Marine Lines, Mumbai 400 020 (Maharashtra), New Marine Lines, Marine Lines, Mumbai, Maharashtra 400020
Other Info - BDZ0001

FAQs

BD-Zadine 100 Injection 1's works by preventing cancer cells from growing. Thereby, it helps treat cancer.

Men should avoid fathering a child whilst on treatment with BD-Zadine 100 Injection 1's. Consult the doctor if you wish to conserve your sperm before starting the treatment. Use effective contraception during the treatment with BD-Zadine 100 Injection 1's and for three months after stopping the treatment.

BD-Zadine 100 Injection 1's may cause a serious immune reaction known as differentiation syndrome. Consult the doctor immediately if you experience fever, rash, difficulty breathing, cough, decreased urine, rapid weight gain, low blood pressure, or swelling of the legs or arms.

Disclaimer

While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.
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Alcohol

Consult your doctor

It is not known if alcohol affects BD-Zadine 100 Injection 1's. Please consult your doctor.

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Pregnancy

Unsafe

Azacitidine belongs to pregnancy category D. BD-Zadine 100 Injection 1's should not be used during pregnancy as it may harm the baby. Consult the doctor immediately if you become pregnant during treatment with BD-Zadine 100 Injection 1's.

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Breast Feeding

Unsafe

It is unknown if Azacitidine passes into breast milk. Breastfeeding is not recommended during treatment with BD-Zadine 100 Injection 1's.

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Driving

Caution

BD-Zadine 100 Injection 1's may cause dizziness and tiredness. Avoid driving or operating machinery if you experience any side effects that might lessen your ability to do so.

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Liver

Caution

If you have a history of liver disease, inform your doctor before receiving BD-Zadine 100 Injection 1's. This medicine should be used with caution in patients with severe pre-existing liver impairment.

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Kidney

Caution

If you have a history of kidney disease, inform your doctor before receiving BD-Zadine 100 Injection 1's. Monitoring patients with kidney impairment is advised.

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Children

Unsafe

BD-Zadine 100 Injection 1's is not recommended for children below 18 years as safety and effectiveness have not been established.

About BD-Zadine 100 Injection 1's

BD-Zadine 100 Injection 1's belongs to the group of medicines called anti-metabolites used in adults with higher-risk myelodysplastic syndromes, chronic myelomonocytic leukaemia, and acute myeloid leukaemia. These conditions affect the bone marrow and could cause problems with normal blood cell production. 
 
BD-Zadine 100 Injection 1's contains Azacitidine, which works by preventing cancer cells from growing. It helps the bone marrow in the production of normal blood cells and kills abnormal cells in the bone marrow.
 
In some cases, BD-Zadine 100 Injection 1's may cause side effects such as nausea, vomiting, diarrhoea, constipation, weakness, headache, and injection site reactions. Most of these side effects may not require medical attention and resolve gradually over time. Do not be reluctant to talk with your doctor if any of the side effects persist or worsen.
 
Do not use BD-Zadine 100 Injection 1's if you are pregnant or breastfeeding. Consult a doctor immediately if you become pregnant during treatment with BD-Zadine 100 Injection 1's. This medicine is not recommended for children as safety and effectiveness have not been established. Inform your doctor about your health condition and medications to rule out any side effects/interactions.

Uses of BD-Zadine 100 Injection 1's

Myelodysplastic syndrome, chronic myelomonocytic leukaemia, and acute myeloid leukaemia.

Medicinal Benefits Mweb

Medicinal Benefits

BD-Zadine 100 Injection 1's belongs to the group of medicines called anti-metabolites used to treat myelodysplastic syndromes, chronic myelomonocytic leukaemia, and acute myeloid leukaemia. BD-Zadine 100 Injection 1's contains Azacitidine, a nucleoside metabolic inhibitor which works by preventing cancer cells from growing. It incorporates into the genetic material of the cells and interferes with the production of new DNA and RNA. This helps correct problems with the maturation and growth of young blood cells in the bone marrow, which causes myelodysplastic disorders.

Directions for Use

BD-Zadine 100 Injection 1's will be administered by a qualified physician; do not self-administer.

Side Effects of BD-Zadine 100 Injection 1's

  • Reduced blood count (red blood count, white blood count, and platelets)
  • Nausea
  • Vomiting
  • Diarrhoea
  • Constipation
  • Headache
  • Tiredness
  • Dizziness
  • Pneumonia
  • Injection site reaction (redness, pain or a skin reaction).

Drug Warnings

Do not use BD-Zadine 100 Injection 1's if you are allergic to any of its components, have advanced liver cancer, or are breastfeeding. Inform the doctor if you have a low number of platelets, red or white blood cells, heart condition or heart attack, lung, kidney or liver diseases. Seek immediate medical attention if you experience symptoms of liver failure (jaundice, abdominal bloating, shaking, drowsiness, and easy bruising), kidney failure (back pain, increased thirst, swelling of legs and feet, reduced passing of water, dizziness, rapid pulse, nausea, vomiting, reduced appetite, confusion, fatigue or restlessness), fever, pneumonia (shortness of breath or chest pain accompanied with fever), low levels of platelets (bleeding such as blood in stools due to bleeding in the stomach), or allergic reaction (rash, difficulty breathing, itching, or swelling of lips).

Drug-Drug Interactions

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AzacitidineYellow fever vaccine
Critical

Drug-Drug Interactions

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AzacitidineYellow fever vaccine
Critical
How does the drug interact with BD-Zadine 100 Injection:
Taking Yellow fever vaccine with BD-Zadine 100 Injection can increase the risk of infection.

How to manage the interaction:
Although there is a possible interaction between BD-Zadine 100 Injection and the Yellow fever vaccine, you can take these medicines together if prescribed by a doctor. If you notice any signs of infection, it's important to contact a doctor right away. Do not stop using any medications without consulting a doctor.
How does the drug interact with BD-Zadine 100 Injection:
The use of fingolimod in conjunction with BD-Zadine 100 Injection may raise the risk of severe infections.

How to manage the interaction:
Co-administration of BD-Zadine 100 Injection with Fingolimod can possibly result in an interaction, but it can be taken if your doctor has advised it. However, Consult a doctor immediately if you have a fever, chills, diarrhoea, sore throat, muscle aches, shortness of breath, blood in phlegm, weight loss, red or irritated skin, body sores, or discomfort or burning during urination. Do not discontinue any medications without consulting a doctor.
AzacitidineEfalizumab
Severe
How does the drug interact with BD-Zadine 100 Injection:
Using efalizumab together with BD-Zadine 100 Injection may increase the risk of serious infections.

How to manage the interaction:
Taking BD-Zadine 100 Injection with Efalizumab together can result in an interaction, but it can be taken if a doctor has advised it. If you have any of these symptoms - complications, infection, fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, pain or burning during urination - make sure to contact a doctor right away. Do not stop using any medications without a doctor's advice.
How does the drug interact with BD-Zadine 100 Injection:
When Etanercept is used with BD-Zadine 100 Injection, the likelihood or severity of infection may increase.

How to manage the interaction:
There may be a possibility of interaction between Etanercept and BD-Zadine 100 Injection, but it can be taken if prescribed by a doctor. However, if you develop fever, chills, diarrhea, sore throat, muscular pains, shortness of breath, blood in phlegm, weight loss, red or irritated skin, body sores, or discomfort or burning during urination, consult a doctor immediately. Do not discontinue any medications without a doctor's advice.
How does the drug interact with BD-Zadine 100 Injection:
Using clozapine together with BD-Zadine 100 Injection can lower white blood cell count and may affect the bone marrow function, that may develop serious infections as a result.

How to manage the interaction:
There may be a possibility of interaction between BD-Zadine 100 Injection and Clozapine, but it can be taken if prescribed by a doctor. However, consult a doctor immediately if you have a fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, blood in phlegm, weight loss, red or irritated skin, body sores, or discomfort or burning during urination. Do not stop using any medications without a doctor's advice.
How does the drug interact with BD-Zadine 100 Injection:
Taking BD-Zadine 100 Injection and leflunomide together may increase the chances of developing severe infections.

How to manage the interaction:
Although there is an interaction between leflunomide and BD-Zadine 100 Injection, they can be taken together if prescribed by a doctor. However, consult a doctor if you experience fatigue, dizziness, lightheadedness, unusual bleeding or bruising, fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, weight loss, red or inflamed skin, body sores, and pain or burning during urination. Do not discontinue any medications without consulting a doctor.
AzacitidineBCG vaccine
Severe
How does the drug interact with BD-Zadine 100 Injection:
Taking BCG vaccine with BD-Zadine 100 Injection can increase the risk of infection.

How to manage the interaction:
Co-administration of BD-Zadine 100 Injection with BCG vaccine can result in an interaction, but it can be taken if a doctor has advised it. If you notice any signs of infection, it's important to contact a doctor right away. Do not stop using any medications without consulting a doctor.
How does the drug interact with BD-Zadine 100 Injection:
Taking thalidomide together with BD-Zadine 100 Injection may increase the risk of blood clots and other complications.

How to manage the interaction:
Although taking thalidomide and BD-Zadine 100 Injection together can result in an interaction, it can be taken if a doctor has prescribed it. However, consult the doctor immediately if you experience symptoms such as chest pain, shortness of breath, difficulty breathing, coughing up blood, sudden loss of vision, pain, redness or swelling in an arm or leg, and numbness or weakness on one side of the body. Do not discontinue any medications without consulting a doctor.
How does the drug interact with BD-Zadine 100 Injection:
Taking BD-Zadine 100 Injection with Teriflunomide can increase the risk of developing serious infections.

How to manage the interaction:
Although taking BD-Zadine 100 Injection and Teriflunomide together can cause an interaction, it can be taken if a doctor has suggested it. However, consult a doctor immediately if you have a fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, blood in phlegm, weight loss, red or irritated skin, body sores, or discomfort or burning during urination. Do not stop using any medications without talking to a doctor.
How does the drug interact with BD-Zadine 100 Injection:
Taking Adalimumab with BD-Zadine 100 Injection may raise the risk of severe infections.

How to manage the interaction:
Taking BD-Zadine 100 Injection with Adalimumab together can result in an interaction, but it can be taken if a doctor has advised it. However, if you have any of these symptom's fever, chills, diarrhea, sore throat, muscle aches, difficulty breathing, weight loss, pain or burning while peeing - make sure to contact a doctor right away. Do not stop using any medications without a doctor's advice.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Drug-Diseases Interactions

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No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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Habit Forming

No

Special Advise

  • Your doctor will recommend blood tests prior to treatment with BD-Zadine 100 Injection 1's and at the start of each cycle to check blood cell count, liver and kidney functioning.
  • Women must use reliable contraception during treatment and for six months after receiving the last dose.
  • Male patients are advised to use effective contraception during treatment and for three months after stopping the treatment.
  • If you are due to undergo any surgery, including dental surgery, inform the doctor/dentist that you are on treatment with BD-Zadine 100 Injection 1's.

Diet & Lifestyle Advise

  • Eat a healthy diet and exercise regularly to maintain proper weight.
  • Avoid smoking and alcohol consumption.
  • Include vegetables and fruits in your diet.
  • Avoid fast food, fried food, processed meats, refined carbs and added sugar.
  • Get optimal sleep; rest well.
  • Drink enough water and eat a balanced diet.

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