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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Sunny S , MBBS
48 Hrs returnable
COD available

Online payment accepted

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Whats That

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Composition :

LEFLUNOMIDE-20MG

Manufacturer/Marketer :

Ankaa Pharmaceutical

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

Therapeutic Class

ANTIRHEUMATICS

Country of origin

India

Manufacturer/Marketer address

6/16 a, d/s jangpura extension, bhogal, delhi-110014, india
Other Info - LEF0056

Author Details

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FAQs

Lefmaa-20Mg Tablet is a disease-modifying antirheumatic drug (DMARD) which stops DNA (genetic material) of the provoked immune system cells required for its survival. Thereby, helps in treating inflammation, redness, and swelling at the damaged site (especially joint).

Lefmaa-20Mg Tablet may cause diarrhoea. Drink plenty of fluids and eat non-spicy food if you experience diarrhoea. If you find blood in stools (tarry stools) or if you experience severe diarrhoea consult your doctor. Do not take anti-diarrheal medicine on your own.

It might take 4-6 weeks before you notice any benefit. In some cases, it might also take 6 months for you to feel the full effect of Lefmaa-20Mg Tablet . Take Lefmaa-20Mg Tablet for as long as your doctor has prescribed to treat your condition effectually.

Inform your doctor if you have liver disease, kidney disease, weak immune system and serious infections like pneumonia, or tuberculosis (TB).

Disclaimer

While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.
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Alcohol

Unsafe

You are recommended to avoid alcohol consumption while taking Lefmaa-20Mg Tablet . Alcohol intake, along with Lefmaa-20Mg Tablet , may cause liver disease.

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Pregnancy

Unsafe

It is not recommended to take Lefmaa-20Mg Tablet while you are pregnant. Lefmaa-20Mg Tablet may cause serious birth defects.

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Breast Feeding

Unsafe

It is not recommended to take Lefmaa-20Mg Tablet while you are breastfeeding. Lefmaa-20Mg Tablet passes into breast milk.

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Driving

Caution

Lefmaa-20Mg Tablet may cause dizziness and tiredness; do not drive or operate heavy machinery if you feel dizzy.

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Liver

Caution

Please consult your doctor if you have liver impairment before taking Lefmaa-20Mg Tablet .

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Kidney

Caution

Please consult your doctor if you have kidney impairment before taking Lefmaa-20Mg Tablet .

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Children

Unsafe

Lefmaa-20Mg Tablet is not approved for children under the age of 18 years.

About Lefmaa-20Mg Tablet

Lefmaa-20Mg Tablet belongs to the group of medicines called 'anti-rheumatic agents' used to relieve symptoms of rheumatoid arthritis and psoriatic arthritis. Rheumatoid arthritis is an auto-immune disease (the body's immune system attacks its tissue) which leads to joint pain and damage. Psoriatic arthritis is a kind of inflammatory arthritis which occurs in patients with psoriasis (red patches of skin with silvery scales). 

Lefmaa-20Mg Tablet contains 'Leflunomide' an isoxazole immunomodulatory agent which works by blocking the formation of genetic material, i.e. DNA required for survival of replicating (dividing) cells of the immune system. As a result, it suppresses the activated immune system to reduce pain, inflammation and swelling. 

Take Lefmaa-20Mg Tablet at the same time every day as prescribed by your doctor. In some cases, Lefmaa-20Mg Tablet may cause common side-effects such as diarrhoea, nausea, stomach pain, indigestion, rash, and hair loss. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side effects persistently.

Do not take Lefmaa-20Mg Tablet if you are pregnant or planning for pregnancy as Lefmaa-20Mg Tablet may cause serious congenital disabilities. Lefmaa-20Mg Tablet should not be taken by breastfeeding mothers as it passes into breast milk. Lefmaa-20Mg Tablet may cause dizziness, so drive with caution. Avoid consuming alcohol along with Lefmaa-20Mg Tablet as it could lead to increased dizziness and liver damage. Lefmaa-20Mg Tablet may make you more susceptible to infections; consult your doctor if you develop any signs of infections such as fever, sore throat, breathlessness, jaundice, unexplained bleeding or bruising.

Uses of Lefmaa-20Mg Tablet

Rheumatoid arthritis, Psoriatic arthritis

Medicinal Benefits Mweb

Medicinal Benefits

Lefmaa-20Mg Tablet belongs to the group of medicines called anti-rheumatic agents used to relieve symptoms of rheumatoid arthritis and psoriatic arthritis. Lefmaa-20Mg Tablet is a disease-modifying antirheumatic drug (DMARDs) which inhibits an enzyme called dihydroorotate dehydrogenase and has antiproliferative activity (suppresses the cell growth). Thereby, helps in treating inflammation, redness, and swelling.

Directions for Use

Take Lefmaa-20Mg Tablet with or without food. Swallow Lefmaa-20Mg Tablet as a whole with water; do not crush or chew it.

Side Effects of Lefmaa-20Mg Tablet

  • Diarrhoea
  • Nausea
  • Stomach pain
  • Indigestion
  • Rash
  • Hair loss

Drug Warnings

Do not take Lefmaa-20Mg Tablet if you are allergic to leflunomide, have severe liverkidney problems, low levels of protein in the blood, immune system problems, bone marrow problems, or serious infections. Lefmaa-20Mg Tablet is not recommended to be used in pregnant women, lactating mothers and people below 18 years of age. Talk to your doctor before taking Lefmaa-20Mg Tablet if you have/had serious infections like interstitial lung disease (inflammation of lungs), tuberculosis (TB), or pneumonia. Lefmaa-20Mg Tablet may cause dizziness, so drive with caution. Lefmaa-20Mg Tablet may make you more susceptible to infections; notify the doctor if you develop infections, sore throat, breathlessness, jaundice, unexplained bleeding or bruising.

Drug-Drug Interactions

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Drug-Drug Interactions

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How does the drug interact with Lefmaa 20 mg Tablet:
Taking Lefmaa 20 mg Tablet with Lisinopril affects the liver and may increase the risk of liver problems.

How to manage the interaction:
Taking Lefmaa 20 mg Tablet with Lisinopril together can possibly result in an interaction, but it can be taken if your doctor has advised it. However, consult the doctor immediately if you experience symptoms such as fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, loss of hunger, weakness, nausea, vomiting, abdominal pain, dark colored urine, light colored stools, and/or yellowing of the skin or eyes. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Lefmaa 20 mg Tablet:
Coadministration of nevirapine and Lefmaa 20 mg Tablet can increase the risk of liver problems.

How to manage the interaction:
Although there is an interaction between Lefmaa 20 mg Tablet and nevirapine, they can be taken together if prescribed by a doctor. However, if you experience fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, less desire to eat, fatigue, nausea, vomiting, abdominal pain, or yellowing of the skin or eyes, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Lefmaa 20 mg Tablet:
When atorvastatin and Lefmaa 20 mg Tablet are taken together it can increase the risk of liver problems.

How to manage the interaction:
Although taking Atorvastatin and Lefmaa 20 mg Tablet together can result in an interaction, they can be taken together if prescribed by a doctor. However, consult a doctor if you experience fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, less desire to eat, fatigue, nausea, vomiting, abdominal pain, and/or yellowing of the skin or eyes. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Lefmaa 20 mg Tablet:
Coadministration of Levofloxacin and Lefmaa 20 mg Tablet can increase the risk of liver issues.

How to manage the interaction:
Although concomitant administration of levofloxacin alongside Lefmaa 20 mg Tablet can result in an interaction, it can be taken if a doctor has advised it. However, if you have a fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, loss of appetite, fatigue, nausea, vomiting, abdominal pain, dark-colored urine, light-colored stools, and/or yellowing of the skin or eyes, contact the doctor right away. Do not discontinue any medications without consulting a doctor.
LeflunomideBinimetinib
Severe
How does the drug interact with Lefmaa 20 mg Tablet:
Lefmaa 20 mg Tablet can cause liver problems, and combining it with other drugs, such as Binimetinib, can raise the risk.

How to manage the interaction:
Taking Lefmaa 20 mg Tablet with Binimetinib together can possibly result in an interaction, but it can be taken if your doctor has advised it. If you notice any of these symptoms - fever, joint pain, rash, or stomach discomfort, contact your doctor right away. Do not stop using any medications without a doctor's advice.
How does the drug interact with Lefmaa 20 mg Tablet:
Co-administration of Lefmaa 20 mg Tablet and Terbinafine can increase the risk or severity of liver problems.

How to manage the interaction:
Although there is an interaction between Lefmaa 20 mg Tablet and terbinafine, they can be taken together if prescribed by a doctor. However, if you experience fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, less desire to eat, fatigue, nausea, vomiting, abdominal pain, or yellowing of the skin or eyes, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Lefmaa 20 mg Tablet:
Co-administration of Lefmaa 20 mg Tablet with Dimethyl fumarate may increase the risk of serious infections. These medications may also lead to liver damage rarely.

How to manage the interaction:
Although there is a possible interaction, Dimethyl fumarate can be taken with Lefmaa 20 mg Tablet if prescribed by the doctor. Consult the prescriber if you experience signs and symptoms of infection like muscle aches, shortness of breath, blood in phlegm, fever, chills, diarrhoea, sore throat, weight loss, red or inflamed skin, b1ody sores, pain or burning during urination. Seek immediate medical attention if you notice signs and symptoms of the liver such as fatigue, nausea, vomiting, fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, loss of appetite, and dark-coloured urine. Do not stop using any medications without talking to a doctor.
How does the drug interact with Lefmaa 20 mg Tablet:
Taking azacitidine and Lefmaa 20 mg Tablet together may increase the chances of developing severe infections.

How to manage the interaction:
Although there is an interaction between Lefmaa 20 mg Tablet and azacitidine, they can be taken together if prescribed by a doctor. However, consult a doctor if you experience fatigue, dizziness, lightheadedness, unusual bleeding or bruising, fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, weight loss, red or inflamed skin, body sores, and pain or burning during urination. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Lefmaa 20 mg Tablet:
Coadministration of Piroxicam and Lefmaa 20 mg Tablet can increase the risk of liver damage.

How to manage the interaction:
Although there is a possible interaction between Lefmaa 20 mg Tablet and Piroxicam, you can take these medicines together if prescribed by a doctor. However, if you have any of the following symptoms: fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, fatigue, lack of hunger, nausea, vomiting, abdominal pain, dark urine, light stools, and/or yellowing of the skin or eyes, consult a doctor immediately. Do not stop using any medications without talking to a doctor.
How does the drug interact with Lefmaa 20 mg Tablet:
Coadministration of Ethambutol with Lefmaa 20 mg Tablet may increase the risk of liver problems.

How to manage the interaction:
Although taking Ethambutol with Lefmaa 20 mg Tablet can result in an interaction, they can be taken together if prescribed by a doctor. However, consult a doctor immediately if you experience fever, joint pain or swelling, skin rash, vomiting, abdominal pain, dark urine, or yellowing of the skin or eyes. Do not discontinue using any medications without consulting a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Drug-Diseases Interactions

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No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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Drug-Drug Interactions Checker List

  • IBUPROFEN
  • NAPROXEN
  • ACETAMINOPHEN
  • ASPIRIN
  • DULOXETINE
  • PREDNISONE
  • CELECOXIB
  • AZATHIOPRINE
  • MELOXICAM
  • METHOTREXATE
  • ETANERCEPT
  • ADALIMUMAB
  • ABATACEPT
  • INFLIXIMAB
  • HYDROXYCHLOROQUINE

Habit Forming

No

Special Advise

Regular blood tests to monitor your liver function after starting Lefmaa-20Mg Tablet , and for every 6-8 weeks are advised.

Diet & Lifestyle Advise

  • Physical activity helps in strengthening muscles and relieves joint stiffness. Gentle activities like 20-30minutes of walking or swimming would be helpful.
  • Performing yoga may also help in improving joint flexibility and pain management.
  • Maintain a healthy weight by performing regular low-strain exercises and eating healthy food.
  • Get adequate sleep as resting the muscles can help in reducing inflammation and swelling.
  • De-stress yourself by meditating, reading books, taking a warm bubble bath or listening to soothing music.
  • Acupuncture, massage and physical therapy may also be helpful.
  • Eat food rich in antioxidants such as berries, spinach, kidney beans, dark chocolate, etc.
  • Foods containing flavonoids help in reducing inflammation. These include soy, berries, broccoli, grapes and green tea.
  • Avoid smoking and alcohol consumption.

Lefmaa-20Mg Tablet Substitute

Always consult your doctor before taking any new medications and supplements

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