apollo
0

Welcome User

Login/Sign Up

Home
Buy Medicines
Lab Tests
Doctor Consult
Circle Membership
Insurance
Blogs
Contact Us
Privacy Policy
Return & Refunds
Need Help
Terms and Conditions
  1. Home
  2. Medicine

  3. Perfecine Tablet

Perfecine Tablet, Pack of 1 Tablet
Written By Santoshini Reddy G , M Pharmacy
Reviewed By Hari Kumar , MBBS
48 Hrs returnable
Know More
COD available

Online payment accepted

rxMedicinePrescription drug

Whats That

tooltip

Composition :

PIRFENIDONE-200MG

Consume Type :

ORAL

Return Policy :

Not Returnable

Therapeutic Class

MISCELLANEOUS

Country of origin

India

Manufacturer/Marketer address

Shop No 7, Ground Floor Near SBI Bank, Raipur Kalan Chandigarh - 160102 India.
Other Info - PE91499

Author Details

Santoshini Reddy GDoctor badge

Written By

Santoshini Reddy G

M Pharmacy

Hari Kumar

Reviewed By

Hari Kumar

MBBS

Last Updated

Aug 20, 2024 | 1:08 PM IST

Doctor imageWe provide you with authentic, trustworthy and relevant information

FAQs

Perfecine Tablet helps in reducing the scarring and swelling in the lungs by decreasing the release/activity of naturally occurring growth factors in the body, thereby helps you breathe better.

Perfecine Tablet might make you photosensitive (sensitivity to sunlight). Avoid exposure to sunlight and sunlamps. Wear SPF 50+ sunscreen and protective clothing to reduce exposure to sunlight. Talk to your doctor if you are taking any medicines known to cause photosensitivity. If you notice any symptoms of photosensitivity, consult a doctor.

Do not discontinue Perfecine Tablet without consulting your doctor. To treat your condition effectually, continue taking Perfecine Tablet for as long as prescribed. Do not be reluctant to speak with your doctor if you experience any difficulty while taking Perfecine Tablet.

Diarrhoea might be a side-effect of Perfecine Tablet. Drink lots of fluids and eat non-spicy food if you experience diarrhoea. If you find blood in stools (tarry stools) or if you have severe diarrhoea, consult your doctor. Do not take anti-diarrheal medicine on your own.

No, avoid smoking prior to the start of the treatment and while taking Perfecine Tablet as smoking might alter the effectiveness of Perfecine Tablet.

Weight loss could occur due to loss of appetite. Maintain proper weight by eating healthy food. Your doctor might monitor your weight whilst taking Perfecine Tablet. Consult your doctor if you notice severe weight loss.

Disclaimer

While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.
bannner image

Alcohol

Caution

It is not known if alcohol interacts with Perfecine Tablet. However, avoid consumption of alcohol while taking Perfecine Tablet as it may cause increased dizziness.

bannner image

Pregnancy

Caution

Please consult your doctor if you have any concerns regarding this; your doctor will prescribe only if the benefits outweigh the risks.

bannner image

Breast Feeding

Caution

Consult your doctor if you are breastfeeding; your doctor will decide whether Perfecine Tablet can be taken by breastfeeding mothers or not.

bannner image

Driving

Caution

Perfecine Tablet might cause dizziness and tiredness. Drive or operate machinery only if you are alert.

bannner image

Liver

Caution

Dose adjustment may be needed. Please consult your doctor if you have a liver impairment or any concerns regarding this. Perfecine Tablet is not recommended for patients with severe hepatic impairment.

bannner image

Kidney

Caution

Dose adjustment may be needed. Please consult your doctor if you have kidney impairment or any concerns. Perfecine Tablet is not recommended for patients with an end-stage renal disease requiring dialysis.

bannner image

Children

Unsafe

Perfecine Tablet is not recommended for children below 18years as the safety and effectiveness has not been established.

Product Substitutes

Reference

  1. https://www.medicines.org.uk/emc/files/pil.3705.pdf
  2. https://www.accessdata.fda.gov/drugsatfda_docs/label/2017/208780s000lbl.pdf
  3. https://www.drugs.com/mtm/pirfenidone.html
  4. https://www.esbriethcp.com/
  5. https://www.uhb.nhs.uk/Downloads/pdf/PiPirfenidone.pdf
  6. https://www.uhs.nhs.uk/Media/UHS-website-2019/Patientinformation/Respiratory/Pirfenidone-patient-information.PDF

About Perfecine Tablet

Perfecine Tablet is an anti-fibrotic medicine used to treat idiopathic pulmonary fibrosis (IPF) in adults. IPF is an irreversible disease that is marked by a progressive decline in lung function. The tissues in the lungs become swollen and scarred over time, due to which it gets difficult to breathe deeply. The scarring makes it hard for the lungs to work properly.
 
Perfecine Tablet contains ‘Pirfenidone’, which helps in reducing the scarring and swelling in the lungs by decreasing the release/activity of naturally occurring growth factors in the body, thereby helps you breathe better. Perfecine Tablet helps in slowing down the progress of idiopathic pulmonary fibrosis. 

In some cases, you may experience certain common side effects such as nausea, tiredness, diarrhoea, indigestion, loss of appetite, headache, and photosensitivity. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side effects persistently.
 
Consult your doctor before taking Perfecine Tablet if you are pregnant or breastfeeding. Perfecine Tablet may cause tiredness and dizziness, so drive with caution. Avoid consuming alcohol with Perfecine Tablet as it could lead to increased dizziness. Perfecine Tablet is not recommended for children below 18 years as safety and effectiveness have not been established. Keep your doctor informed about your health condition and medicines to rule out any side effects.

Uses of Perfecine Tablet

Idiopathic pulmonary fibrosis

Medicinal Benefits Mweb

Medicinal Benefits

Perfecine Tablet is an anti-fibrotic medicine used to treat idiopathic pulmonary fibrosis (IPF) in adults. Perfecine Tablet can help effectively slow the rate of lung function decline by 50%. Perfecine Tablet helps reduce the scarring and swelling in the lungs by decreasing the release/activity of naturally occurring growth factors in the body, thereby helps you breathe better. Perfecine Tablet helps in slowing down the progress of idiopathic pulmonary fibrosis.

Directions for Use

Take Perfecine Tablet with food. Swallow Perfecine Tablet as a whole with a glass of water; do not chew or crush it.

Side Effects of Perfecine Tablet

  • Nausea
  • Tiredness
  • Diarrhoea
  • Indigestion/Stomach upset
  • Loss of appetite
  • Headache
  • Photosensitivity

Drug Warnings

Do not take Perfecine Tablet if you are allergic to any of its components; if you have a severe or end-stage liver impairment or kidney disease requiring dialysis; if you are taking fluvoxamine (anti-depressant). Inform your doctor if you are taking any medicines that might make you photosensitive, if you smoke or have kidney or liver problems. Consult your doctor before taking Perfecine Tablet if you are pregnant or breastfeeding. Perfecine Tablet may cause tiredness and dizziness, so drive with caution. Avoid consuming alcohol with Perfecine Tablet as it could lead to increased dizziness. Perfecine Tablet is not recommended for children below 18 years as safety and effectiveness have not been established.

Drug-Drug Interactions

verifiedApollotooltip
PirfenidoneRifampicin
Critical
PirfenidoneCarbamazepine
Critical

Drug-Drug Interactions

Login/Sign Up

PirfenidoneRifampicin
Critical
How does the drug interact with Perfecine Tablet:
Taking Perfecine Tablet with rifampicin can reduce the levels and effects of Perfecine Tablet

How to manage the interaction:
Although there is an interaction between Perfecine Tablet and rifampicin, they can be taken together if prescribed by a doctor. However, if you experience any unusual symptoms, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
PirfenidoneCarbamazepine
Critical
How does the drug interact with Perfecine Tablet:
Taking Perfecine Tablet with Carbamazepine it reduces the levels and effects of Perfecine Tablet.

How to manage the interaction:
Taking Perfecine Tablet with Carbamazepine is not recommended but can be taken if prescribed by the doctor. However, if you experience any unusual symptoms contact a doctor immediately. Do not stop using any medications without talking to a doctor.
PirfenidonePhenobarbital
Critical
How does the drug interact with Perfecine Tablet:
When Perfecine Tablet is taken with Phenobarbital, it can decrease the effects of Perfecine Tablet.

How to manage the interaction:
Taking Perfecine Tablet with Phenobarbital is not recommended but can be taken if prescribed by the doctor. Do not discontinue any medication without consulting a doctor.
PirfenidonePrimidone
Critical
How does the drug interact with Perfecine Tablet:
Coadministration of Perfecine Tablet with primidone can reduce levels and the effects of Perfecine Tablet.

How to manage the interaction:
Although there is an interaction between Perfecine Tablet and primidone, they can be taken together if advised by your doctor. However, if you experience any unusual symptoms, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
PirfenidoneLomitapide
Severe
How does the drug interact with Perfecine Tablet:
Taking Lomitapide with Perfecine Tablet may increase the risk of liver damage

How to manage the interaction:
There may be a possibility of interaction between Perfecine Tablet and Lomitapide, but it can be taken if prescribed by a doctor. However, if you have any of the following symptoms: fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, fatigue, lack of appetite, nausea, vomiting, abdominal pain, dark urine, light stools, and/or yellowing of the skin or eyes, consult a doctor immediately. Do not discontinue any medications without a doctor's advice.
PirfenidoneAminolevulinic acid
Severe
How does the drug interact with Perfecine Tablet:
Co-administration of Aminolevulinic acid and Perfecine Tablet may increase the risk of skin burn.

How to manage the interaction:
There may be a possibility of interaction between Perfecine Tablet and Aminolevulinic acid, but it can be taken if prescribed by a doctor. Avoid exposure of the eyes and skin to sunlight or bright indoor lights for 48 hours after treatment. Do not discontinue any medications without consulting a doctor.
PirfenidoneCiprofloxacin
Severe
How does the drug interact with Perfecine Tablet:
When ciprofloxacin is taken Perfecine Tablet, the blood levels of Perfecine Tablet may increase, which may lead to side effects.

How to manage the interaction:
Although taking ciprofloxacin and Perfecine Tablet together can possibly result in an interaction, it can be taken if your doctor has prescribed it. However, if you have any of the following symptoms, fever, chills, joint pain or swelling, unusual bleeding or wounds, skin rash, itching, tiredness, nausea, vomiting, dark urine, light stools, and/or yellowing of the skin or eyes, consult a doctor. Do not discontinue any medications without a doctor's advice.
PirfenidoneKetoconazole
Severe
How does the drug interact with Perfecine Tablet:
Coadministration of Ketoconazole and Perfecine Tablet may increase the risk of liver damage.

How to manage the interaction:
Although taking Ketoconazole and Perfecine Tablet together can result in an interaction, it can be taken if a doctor has prescribed it. However, if you have any of the following symptoms: fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, fatigue, lack of appetite, nausea, vomiting, abdominal pain, dark urine, light stools, and/or yellowing of the skin or eyes, consult the doctor immediately. Do not discontinue any medications without a doctor's advice.
PirfenidoneRucaparib
Severe
How does the drug interact with Perfecine Tablet:
Taking Perfecine Tablet with Rucaparib can increase the risk or severity of its side effects such as liver disease or gastric problems.

How to manage the interaction:
Co-administration of Perfecine Tablet with Rucaparib can possibly result in an interaction, but it can be taken if your doctor has advised it. However, if you have any of the following symptoms: fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, fatigue, lack of appetite, nausea, vomiting, abdominal pain, dark urine, light stools, and/or yellowing of the skin or eyes, consult a doctor immediately.
PirfenidoneMibefradil
Severe
How does the drug interact with Perfecine Tablet:
Taking Perfecine Tablet with Mibefradil can increase the risk or severity of its side effects such as liver disease or gastric problems.

How to manage the interaction:
There may be a possibility of interaction between Perfecine Tablet and Mibefradil, but it can be taken if prescribed by a doctor. However, if you have any of the following symptoms: fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, fatigue, lack of appetite, nausea, vomiting, abdominal pain, dark urine, light stools, and/or yellowing of the skin or eyes, consult a doctor immediately.

Drug-Food Interactions

verifiedApollotooltip
PIRFENIDONE-200MGGrapefruit and Grapefruit Juice
Moderate

Drug-Food Interactions

Login/Sign Up

PIRFENIDONE-200MGGrapefruit and Grapefruit Juice
Moderate
Common Foods to Avoid:
Grapefruit Juice, Grapefruit

How to manage the interaction:
Taking grape fruit and its products while using Perfecine Tablet can increase the risk of side effects. Avoid grape fruit and its products during treatment with Perfecine Tablet.

Drug-Diseases Interactions

verifiedApollotooltip
No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

Login/Sign Up

Drug-Drug Interactions Checker List

  • FLUVOXAMINE
  • CIPROFLOXACIN
  • ENOXACIN
  • RIFAMPICIN
  • AMIODARONE
  • PROPAFENONE
  • OMEPRAZOLE

Habit Forming

No

Special Advise

  • Your doctor may advise liver function tests prior to the start of the treatment.
  • Regular blood tests are advised at the start of treatment with Perfecine Tablet and monthly for every 6 months, and then for every 3 months thereafter to check the liver functioning.

Diet & Lifestyle Advise

  • Watch out for triggers that make the cough worse, such as smoke, foods, air-conditioning, high altitude, etc.
  • Exercise moderately. Eat healthily.
  • Follow the pulmonary rehabilitation program. It includes exercise, disease education, and group therapy.
  • Quit smoking.
  • Get ample rest.
  • Include green leafy vegetables, sweet potatoes, broccoli, tomatoes, carrots, mangoes, citrus fruits, berries, and cocoa.
  • Lean proteins such as fish, meat, and poultry are the best.
  • Hydration is important. Drink plenty of water, herbal tea, and fruit juices.
  • Avoid processed and refined foods.

Perfecine Tablet Substitute

Substitutes safety advice

Have a query?