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  5. I have been diagnosed with myasthenia gravis for 1.5 years. Initially, my ocular symptoms, such as drooping eyelids, were controlled with Gravitor (Pyridostigmine). I am currently taking 60 mg of Gravitor along with multivitamin supplements and monitoring my total leukocyte count and hemoglobin. My doctor prescribed Azoran (Azathioprine). What should be the next steps, and are there alternative or additional treatment options if my symptoms persist?

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I have been diagnosed with myasthenia gravis for 1.5 years. Initially, my ocular symptoms, such as drooping eyelids, were controlled with Gravitor (Pyridostigmine). I am currently taking 60 mg of Gravitor along with multivitamin supplements and monitoring my total leukocyte count and hemoglobin. My doctor prescribed Azoran (Azathioprine). What should be the next steps, and are there alternative or additional treatment options if my symptoms persist?

Asked by Male, 45 · 2 months ago

The next step is to follow your doctor’s plan to introduce a long-term immunosuppressive therapy, which can help control symptoms and reduce reliance on short-term medications. Since these therapies may take several months to show full effect, continue your current symptomatic treatment as advised and maintain regular monitoring of blood counts to detect potential side effects. If symptoms persist or the therapy is not fully effective, your doctor may consider alternative or additional treatment options, including other immunomodulatory strategies or advanced therapies, tailored to your condition. Continuous follow-up with a neurologist is essential to adjust treatment safely and effectively.
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  1. Current Treatment Overview

    • Pyridostigmine (Gravitor) enhances nerve-muscle communication, alleviating symptoms.
    • Azathioprine (Azoran) acts as an immunosuppressant to reduce autoimmune activity.
  2. Monitoring and Follow-Up

    • Regular blood tests are crucial to monitor Azathioprine's side effects on blood cells.
    • Schedule clinical evaluations to adjust treatment based on symptom control.
  3. Alternative Treatment Options

    • Consider corticosteroids like Prednisolone for rapid immune suppression if needed.
    • Explore other immunosuppressants (e.g., Mycophenolate mofetil) if Azathioprine is unsuitable.
    • Thymectomy may be beneficial, especially with thymoma presence.
    • IVIG or plasmapheresis can provide quick relief during exacerbations.
  4. Lifestyle and Supportive Measures

    • Manage fatigue and avoid symptom triggers.
    • Engage in physical therapy and supportive care.
  5. Specialist Coordination

    • Collaborate with a neurologist specializing in myasthenia gravis.
    • Involve other specialists for comprehensive management.

Answered 2 months ago

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