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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
48 Hrs returnable
COD available

Online payment accepted

rxMedicinePrescription drug

Whats That

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Synonym :

ACICLOVIR

Composition :

ACYCLOVIR-5%W/W

Manufacturer/Marketer :

East African Overseas (I) Pvt Ltd

Consume Type :

TOPICAL

Return Policy :

Not Returnable

Therapeutic Class

ANTIVIRALS

Country of origin

India
Other Info - AC62129

FAQs

Acloriv 5% Cream contains acyclovir, it exerts antiviral activity against herpes simplex viruses (HSV) by interfering with DNA synthesis and limiting viral replication. Thus it treats recurrent herpes labialis (cold sores).

Acloriv 5% Cream is contraindicated in patients allergic to acyclovir, valacyclovir or any component of the formulation.

In rare cases, angioedema (the swelling of the deeper layers of the skin, caused by a build-up of fluid) has been identified in Postmarketing Experience.

Systemic medication interactions are unlikely due to Acloriv 5% Cream's low systemic absorption. Clinical experience has revealed no interactions caused by the concurrent topical or systemic administration of other medicines with Acloriv 5% Cream.

Disclaimer

While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.
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Alcohol

Not applicable

No interactions were found. However, avoid alcohol consumption as it can irritate the mouth.

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Pregnancy

Safe if prescribed

Acloriv 5% Cream is generally safe to be used in pregnancy. If you have concerns, discuss them with your doctor before using the Acloriv 5% Cream.

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Breast Feeding

Safe if prescribed

Acloriv 5% Cream is generally safe to be used while breastfeeding. If you have concerns, discuss them with your doctor before using the Acloriv 5% Cream.

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Driving

Not applicable

Acloriv 5% Cream usually does not impact your ability to drive or operate machinery.

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Liver

Safe if prescribed

No interactions were found. Acloriv 5% Cream can be used safely due to its minimal systemic absorption.

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Kidney

Safe if prescribed

No interactions were found. Acloriv 5% Cream can be used safely due to its minimal systemic absorption.

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Children

Caution

Acloriv 5% Cream is not recommended for use in children below 12 years.

About Acloriv 5% Cream

Acloriv 5% Cream belongs to the class of 'antivirals' that is generally used to treat recurrent herpes labialis (cold sores) in immunocompetent adults and adolescents aged 12 and up. Recurrent herpes simplex labialis, often known as oral herpes, is a disorder caused by the herpes simplex virus that affects the lips. It's a common and contagious illness that spreads quickly.

Acloriv 5% Cream contains acyclovir, it exerts antiviral activity against herpes simplex viruses (HSV) by interfering with DNA synthesis and limiting viral replication.

Acloriv 5% Cream is solely for the topical treatment of recurrent HSV lesions on the lips and face. It should be used as prescribed by your doctor. Dry lips, desquamation (scale off or peel off), dryness of skin, cracked lips, scorching skin, pruritus, flakiness of skin, and stinging on the skin were the most prevalent adverse effects to Acloriv 5% Cream at the site of topical administration. These side effects may not occur in every patient who takes this drug and will fade over time. Please notify your doctor if the side effects last longer or worsen.

Acloriv 5% Cream is restricted for use in people who are sensitive to acyclovir, valacyclovir or any component of the formulation. Acloriv 5% Cream should not be applied on mucous membranes including in the eye or inside the mouth or nose. The effect of Acloriv 5% Cream has not been established in immunocompromised patients. Before using Acloriv 5% Cream, consult your doctor if you are pregnant, planning to become pregnant, or breastfeeding. Acloriv 5% Cream is recommended not for use in children below 12 years.

Uses of Acloriv 5% Cream

Recurrent herpes labialis (cold sores)

Medicinal Benefits Mweb

Medicinal Benefits

Acloriv 5% Cream treats viral infections caused by the herpes simplex and varicella-zoster viruses. It consists of Acyclovir, an antiviral drug. It works by killing and stopping the growth of the virus. Acloriv 5% Cream effectively treats herpes simplex encephalitis (brain inflammation by herpes simplex virus) and neonatal herpes simplex virus infection. Acloriv 5% Cream is also useful in preventing the reactivation of the cytomegalovirus infection in seropositive (showing a positive result of a blood test for a particular antibody) patients following bone marrow transplantation.

Directions for Use

Take the prescribed amount and apply it to the affected area(s) for 4 days, 5 times a day.

Side Effects of Acloriv 5% Cream

  • Dry lips
  • Desquamation (scale off)
  • Dryness of skin
  • Cracked lips
  • Burning skin
  • Pruritus
  • Flakiness of skin
  • Stinging on skin

Drug Warnings

Inform your doctor if you use prescription, non-prescription drugs, and herbal products before using Acloriv 5% Cream. And also let your doctor know if you are allergic to any components in Acloriv 5% Cream. Inform your doctor of your medical history before starting Acloriv 5% Cream. Though it is safe to use during pregnancy or breastfeeding, you must inform the healthcare provider before using the Acloriv 5% Cream.

Drug-Drug Interactions

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No Drug - Drug interactions found in our data. We may lack specific data on this medicine and are actively working to update our database. Consult your doctor for personalized advice

Drug-Drug Interactions

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Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Drug-Diseases Interactions

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ACYCLOVIR-5%W/WOther disorders of kidney and ureter, not elsewhere classified
Severe
ACYCLOVIR-5%W/WVolume depletion
Moderate

Drug-Diseases Interactions

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ACYCLOVIR-5%W/WOther disorders of kidney and ureter, not elsewhere classified
Severe
How does the disease interact with Acloriv 5% Cream:
Acyclovir should be used with caution to patients who have impaired kidney function. In patients with moderate to severe renal impairment, dosage modifications are advised.

How to manage the interaction:
The use of Acloriv 5% Cream in kidney disease patients is not advised as it may increase the severity of kidney disease. Your doctor may adjust the dosing according to the severity of your kidney disease.
ACYCLOVIR-5%W/WVolume depletion
Moderate
How does the disease interact with Acloriv 5% Cream:
Patients who are dehydrated may be more susceptible to nephrotoxicity from using acyclovir. Acyclovir should be infused intravenously over the course of an hour, along with appropriate hydration.

How to manage the interaction:
Acloriv 5% Cream is excreted through the kidneys, dehydration may cause damage to kidney functions. Acloriv 5% Cream infusion over an hour is recommended in dehydrated patients. Urine output should be monitored.
ACYCLOVIR-5%W/WCare involving dialysis
Moderate
How does the disease interact with Acloriv 5% Cream:
Hemodialysis effectively removes acyclovir from the body. Following 6 hours of dialysis, it has been demonstrated that plasma levels of acyclovir decrease by 60%. After hemodialysis, acyclovir should be administered. If not, a second dosage might be administered following each hemodialysis session.

How to manage the interaction:
Patients undergoing hemodialysis should be given Acloriv 5% Cream after completing hemodialysis as hemodialysis removes 60% of Acloriv 5% Cream from the body.

Habit Forming

No

Special Advise

  • Take proper precautions if you are infected with herpes to prevent the spread of infection to others.

Diet & Lifestyle Advise

  • Choose foods high in protein. Ground meats, eggs, cottage cheese, yoghurt, custard, beans, lentils, and smoothies are examples of protein-rich soft foods.
  • Consume modest, regular meals. It may be easier for you to consume fewer portions at a time.
  • Drink through a straw. This can assist in moving foods past the unpleasant sores in your mouth.
  • Every day, drink at least 8-10 eight-ounce glasses of water. Drink fluids in between meals.
  • Citrus fruits and juices, salty or spicy foods, and acidic foods like tomatoes are all things to avoid if you have mouth sores.
  • Do not consume carbonated or caffeinated beverages, beer, wine, liquor, or any other sort of alcohol.
  • Avoid alcohol. Alcohol can irritate the mouth.
  • Hot foods can induce tongue and throat irritation.
  • Maintain good oral hygiene. Rinse your mouth numerous times every day.
  • Use alcohol-free mouthwash. A painful mouth is exacerbated by alcohol.
  • Use a toothbrush with gentle bristles.
  • Avoid smoking, cigars, and tobacco products.

Acloriv 5% Cream Substitute

Always consult your doctor before taking any new medications and supplements

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