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  1. Home
  2. Medicine

  3. Herpesafe Cream

Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
48 Hrs returnable
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COD available

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Herpesafe Cream, Pack of 1 Cream
Herpesafe Cream, Pack of 1 Cream
rxMedicinePrescription drug

Whats That

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Synonym :

ACICLOVIR

Composition :

ACYCLOVIR-5%W/W

Manufacturer/Marketer :

Alkem Laboratories Ltd

Consume Type :

TOPICAL

Return Policy :

Not Returnable

Therapeutic Class

ANTIVIRALS

Country of origin

India
Other Info - HE20949

Author Details

Bayyarapu Mahesh KumarDoctor badge

Written By

Bayyarapu Mahesh Kumar

M Pharmacy

Dr Aneela SiddabathuniDoctor badge

Reviewed By

Dr Aneela Siddabathuni

MPharma., PhD

Last Updated

Aug 20, 2024 | 1:15 PM IST

Doctor imageWe provide you with authentic, trustworthy and relevant information

FAQs

Herpesafe Cream contains acyclovir, it exerts antiviral activity against herpes simplex viruses (HSV) by interfering with DNA synthesis and limiting viral replication. Thus it treats recurrent herpes labialis (cold sores).

Herpesafe Cream is contraindicated in patients allergic to acyclovir, valacyclovir or any component of the formulation.

In rare cases, angioedema (the swelling of the deeper layers of the skin, caused by a build-up of fluid) has been identified in Postmarketing Experience.

Systemic medication interactions are unlikely due to Herpesafe Cream's low systemic absorption. Clinical experience has revealed no interactions caused by the concurrent topical or systemic administration of other medicines with Herpesafe Cream.

Disclaimer

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Alcohol

Not applicable

No interactions were found. However, avoid alcohol consumption as it can irritate the mouth.

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Pregnancy

Safe if prescribed

Herpesafe Cream is generally safe to be used in pregnancy. If you have concerns, discuss them with your doctor before using the Herpesafe Cream.

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Breast Feeding

Safe if prescribed

Herpesafe Cream is generally safe to be used while breastfeeding. If you have concerns, discuss them with your doctor before using the Herpesafe Cream.

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Driving

Not applicable

Herpesafe Cream usually does not impact your ability to drive or operate machinery.

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Liver

Safe if prescribed

No interactions were found. Herpesafe Cream can be used safely due to its minimal systemic absorption.

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Kidney

Safe if prescribed

No interactions were found. Herpesafe Cream can be used safely due to its minimal systemic absorption.

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Children

Caution

Herpesafe Cream is not recommended for use in children below 12 years.

Product Substitutes

Reference

  1. https://www.accessdata.fda.gov/drugsatfda_docs/label/2020/021478s010lbl.pdf
  2. https://www.lls.org/sites/default/files/National/USA/Pdf/PearlPoint/PearlPoint_Nutrition_Tips_for_Managing_Sore_Mouth__Throat__and_Tongue.pdf

About Herpesafe Cream

Herpesafe Cream belongs to the class of 'antivirals' that is generally used to treat recurrent herpes labialis (cold sores) in immunocompetent adults and adolescents aged 12 and up. Recurrent herpes simplex labialis, often known as oral herpes, is a disorder caused by the herpes simplex virus that affects the lips. It's a common and contagious illness that spreads quickly.

Herpesafe Cream contains acyclovir, it exerts antiviral activity against herpes simplex viruses (HSV) by interfering with DNA synthesis and limiting viral replication.

Herpesafe Cream is solely for the topical treatment of recurrent HSV lesions on the lips and face. It should be used as prescribed by your doctor. Dry lips, desquamation (scale off or peel off), dryness of skin, cracked lips, scorching skin, pruritus, flakiness of skin, and stinging on the skin were the most prevalent adverse effects to Herpesafe Cream at the site of topical administration. These side effects may not occur in every patient who takes this drug and will fade over time. Please notify your doctor if the side effects last longer or worsen.

Herpesafe Cream is restricted for use in people who are sensitive to acyclovir, valacyclovir or any component of the formulation. Herpesafe Cream should not be applied on mucous membranes including in the eye or inside the mouth or nose. The effect of Herpesafe Cream has not been established in immunocompromised patients. Before using Herpesafe Cream, consult your doctor if you are pregnant, planning to become pregnant, or breastfeeding. Herpesafe Cream is recommended not for use in children below 12 years.

Uses of Herpesafe Cream

Recurrent herpes labialis (cold sores)

Medicinal Benefits Mweb

Medicinal Benefits

Herpesafe Cream treats viral infections caused by the herpes simplex and varicella-zoster viruses. It consists of Acyclovir, an antiviral drug. It works by killing and stopping the growth of the virus. Herpesafe Cream effectively treats herpes simplex encephalitis (brain inflammation by herpes simplex virus) and neonatal herpes simplex virus infection. Herpesafe Cream is also useful in preventing the reactivation of the cytomegalovirus infection in seropositive (showing a positive result of a blood test for a particular antibody) patients following bone marrow transplantation.

Directions for Use

Take the prescribed amount and apply it to the affected area(s) for 4 days, 5 times a day.

Side Effects of Herpesafe Cream

  • Dry lips
  • Desquamation (scale off)
  • Dryness of skin
  • Cracked lips
  • Burning skin
  • Pruritus
  • Flakiness of skin
  • Stinging on skin

Drug Warnings

Inform your doctor if you use prescription, non-prescription drugs, and herbal products before using Herpesafe Cream. And also let your doctor know if you are allergic to any components in Herpesafe Cream. Inform your doctor of your medical history before starting Herpesafe Cream. Though it is safe to use during pregnancy or breastfeeding, you must inform the healthcare provider before using the Herpesafe Cream.

Drug-Drug Interactions

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No Drug - Drug interactions found in our data. We may lack specific data on this medicine and are actively working to update our database. Consult your doctor for personalized advice

Drug-Drug Interactions

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Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Drug-Diseases Interactions

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ACYCLOVIR-5%W/WOther disorders of kidney and ureter, not elsewhere classified
Severe
ACYCLOVIR-5%W/WVolume depletion
Moderate

Drug-Diseases Interactions

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ACYCLOVIR-5%W/WOther disorders of kidney and ureter, not elsewhere classified
Severe
How does the disease interact with Herpesafe Cream:
Acyclovir should be used with caution to patients who have impaired kidney function. In patients with moderate to severe renal impairment, dosage modifications are advised.

How to manage the interaction:
The use of Herpesafe Cream in kidney disease patients is not advised as it may increase the severity of kidney disease. Your doctor may adjust the dosing according to the severity of your kidney disease.
ACYCLOVIR-5%W/WVolume depletion
Moderate
How does the disease interact with Herpesafe Cream:
Patients who are dehydrated may be more susceptible to nephrotoxicity from using acyclovir. Acyclovir should be infused intravenously over the course of an hour, along with appropriate hydration.

How to manage the interaction:
Herpesafe Cream is excreted through the kidneys, dehydration may cause damage to kidney functions. Herpesafe Cream infusion over an hour is recommended in dehydrated patients. Urine output should be monitored.
ACYCLOVIR-5%W/WCare involving dialysis
Moderate
How does the disease interact with Herpesafe Cream:
Hemodialysis effectively removes acyclovir from the body. Following 6 hours of dialysis, it has been demonstrated that plasma levels of acyclovir decrease by 60%. After hemodialysis, acyclovir should be administered. If not, a second dosage might be administered following each hemodialysis session.

How to manage the interaction:
Patients undergoing hemodialysis should be given Herpesafe Cream after completing hemodialysis as hemodialysis removes 60% of Herpesafe Cream from the body.

Habit Forming

No

Special Advise

  • Take proper precautions if you are infected with herpes to prevent the spread of infection to others.

Diet & Lifestyle Advise

  • Choose foods high in protein. Ground meats, eggs, cottage cheese, yoghurt, custard, beans, lentils, and smoothies are examples of protein-rich soft foods.
  • Consume modest, regular meals. It may be easier for you to consume fewer portions at a time.
  • Drink through a straw. This can assist in moving foods past the unpleasant sores in your mouth.
  • Every day, drink at least 8-10 eight-ounce glasses of water. Drink fluids in between meals.
  • Citrus fruits and juices, salty or spicy foods, and acidic foods like tomatoes are all things to avoid if you have mouth sores.
  • Do not consume carbonated or caffeinated beverages, beer, wine, liquor, or any other sort of alcohol.
  • Avoid alcohol. Alcohol can irritate the mouth.
  • Hot foods can induce tongue and throat irritation.
  • Maintain good oral hygiene. Rinse your mouth numerous times every day.
  • Use alcohol-free mouthwash. A painful mouth is exacerbated by alcohol.
  • Use a toothbrush with gentle bristles.
  • Avoid smoking, cigars, and tobacco products.

Herpesafe Cream Substitute

Always consult your doctor before taking any new medications and supplements

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  • Acylab 5% Cream

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    ₹7.65per tablet
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  • Elcovir Cream 5 Gm

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