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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Sunny S , MBBS
48 Hrs returnable
COD available

Online payment accepted

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Whats That

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Composition :

LEFLUNOMIDE-20MG

Manufacturer/Marketer :

Hanskri Healthcare

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

Therapeutic Class

ANTIRHEUMATICS

Country of origin

India

Manufacturer/Marketer address

G-30/113, Sector - 3 Rohini, Delhi - 110085
Other Info - LEF0087

Author Details

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FAQs

Lefuhans-20 Tablet is a disease-modifying antirheumatic drug (DMARD) which stops DNA (genetic material) of the provoked immune system cells required for its survival. Thereby, helps in treating inflammation, redness, and swelling at the damaged site (especially joint).

Lefuhans-20 Tablet may cause diarrhoea. Drink plenty of fluids and eat non-spicy food if you experience diarrhoea. If you find blood in stools (tarry stools) or if you experience severe diarrhoea consult your doctor. Do not take anti-diarrheal medicine on your own.

It might take 4-6 weeks before you notice any benefit. In some cases, it might also take 6 months for you to feel the full effect of Lefuhans-20 Tablet . Take Lefuhans-20 Tablet for as long as your doctor has prescribed to treat your condition effectually.

Inform your doctor if you have liver disease, kidney disease, weak immune system and serious infections like pneumonia, or tuberculosis (TB).

Disclaimer

While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.
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Alcohol

Unsafe

You are recommended to avoid alcohol consumption while taking Lefuhans-20 Tablet . Alcohol intake, along with Lefuhans-20 Tablet , may cause liver disease.

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Pregnancy

Unsafe

It is not recommended to take Lefuhans-20 Tablet while you are pregnant. Lefuhans-20 Tablet may cause serious birth defects.

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Breast Feeding

Unsafe

It is not recommended to take Lefuhans-20 Tablet while you are breastfeeding. Lefuhans-20 Tablet passes into breast milk.

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Driving

Caution

Lefuhans-20 Tablet may cause dizziness and tiredness; do not drive or operate heavy machinery if you feel dizzy.

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Liver

Caution

Please consult your doctor if you have liver impairment before taking Lefuhans-20 Tablet .

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Kidney

Caution

Please consult your doctor if you have kidney impairment before taking Lefuhans-20 Tablet .

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Children

Unsafe

Lefuhans-20 Tablet is not approved for children under the age of 18 years.

About Lefuhans-20 Tablet

Lefuhans-20 Tablet belongs to the group of medicines called 'anti-rheumatic agents' used to relieve symptoms of rheumatoid arthritis and psoriatic arthritis. Rheumatoid arthritis is an auto-immune disease (the body's immune system attacks its tissue) which leads to joint pain and damage. Psoriatic arthritis is a kind of inflammatory arthritis which occurs in patients with psoriasis (red patches of skin with silvery scales). 

Lefuhans-20 Tablet contains 'Leflunomide' an isoxazole immunomodulatory agent which works by blocking the formation of genetic material, i.e. DNA required for survival of replicating (dividing) cells of the immune system. As a result, it suppresses the activated immune system to reduce pain, inflammation and swelling. 

Take Lefuhans-20 Tablet at the same time every day as prescribed by your doctor. In some cases, Lefuhans-20 Tablet may cause common side-effects such as diarrhoea, nausea, stomach pain, indigestion, rash, and hair loss. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side effects persistently.

Do not take Lefuhans-20 Tablet if you are pregnant or planning for pregnancy as Lefuhans-20 Tablet may cause serious congenital disabilities. Lefuhans-20 Tablet should not be taken by breastfeeding mothers as it passes into breast milk. Lefuhans-20 Tablet may cause dizziness, so drive with caution. Avoid consuming alcohol along with Lefuhans-20 Tablet as it could lead to increased dizziness and liver damage. Lefuhans-20 Tablet may make you more susceptible to infections; consult your doctor if you develop any signs of infections such as fever, sore throat, breathlessness, jaundice, unexplained bleeding or bruising.

Uses of Lefuhans-20 Tablet

Rheumatoid arthritis, Psoriatic arthritis

Medicinal Benefits Mweb

Medicinal Benefits

Lefuhans-20 Tablet belongs to the group of medicines called anti-rheumatic agents used to relieve symptoms of rheumatoid arthritis and psoriatic arthritis. Lefuhans-20 Tablet is a disease-modifying antirheumatic drug (DMARDs) which inhibits an enzyme called dihydroorotate dehydrogenase and has antiproliferative activity (suppresses the cell growth). Thereby, helps in treating inflammation, redness, and swelling.

Directions for Use

Take Lefuhans-20 Tablet with or without food. Swallow Lefuhans-20 Tablet as a whole with water; do not crush or chew it.

Side Effects of Lefuhans-20 Tablet

  • Diarrhoea
  • Nausea
  • Stomach pain
  • Indigestion
  • Rash
  • Hair loss

Drug Warnings

Do not take Lefuhans-20 Tablet if you are allergic to leflunomide, have severe liverkidney problems, low levels of protein in the blood, immune system problems, bone marrow problems, or serious infections. Lefuhans-20 Tablet is not recommended to be used in pregnant women, lactating mothers and people below 18 years of age. Talk to your doctor before taking Lefuhans-20 Tablet if you have/had serious infections like interstitial lung disease (inflammation of lungs), tuberculosis (TB), or pneumonia. Lefuhans-20 Tablet may cause dizziness, so drive with caution. Lefuhans-20 Tablet may make you more susceptible to infections; notify the doctor if you develop infections, sore throat, breathlessness, jaundice, unexplained bleeding or bruising.

Drug-Drug Interactions

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LeflunomideBrigatinib
Severe

Drug-Drug Interactions

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LeflunomideBrigatinib
Severe
How does the drug interact with Lefuhans-20 Tablet:
Brigatinib can cause higher levels of Lefuhans-20 Tablet in the blood by reducing its excretion.

How to manage the interaction:
There may be a possibility of interaction between Lefuhans-20 Tablet and Brigatinib, but it can be taken if prescribed by a doctor. If you notice symptoms like fever, chills, sore throat, or muscle aches, contact your doctor immediately. Other symptoms to look out for include diarrhea, shortness of breath, weight loss, and pain or burning while urinating." Do not discontinue any medications without consulting your doctor.
How does the drug interact with Lefuhans-20 Tablet:
Taking Lefuhans-20 Tablet with nilotinib can increase the risk of serious infections and liver problems.

How to manage the interaction:
Taking Lefuhans-20 Tablet and nilotinib together can lead to an interaction, it can be taken if advised by your doctor. However, if you experience diarrhea, sore throat, muscle aches, shortness of breath, weight loss, red or inflamed skin, body sores, pain or burning during urination, fever, chills, joint pain or swelling, unusual bleeding, fatigue, nausea, vomiting, and/or yellowing of the skin or eyes, contact your doctor immediately. Do not discontinue any medications without first consulting your doctor.
How does the drug interact with Lefuhans-20 Tablet:
Coadministration of Naproxen and Lefuhans-20 Tablet can increase the risk or severity of liver problems.

How to manage the interaction:
Taking Naproxen and Lefuhans-20 Tablet together can result in an interaction, they can be taken together if prescribed by a doctor. However, if you experience fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, less desire to eat, fatigue, nausea, vomiting, abdominal pain, or yellowing of the skin or eyes, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Lefuhans-20 Tablet:
The combined use of Lefuhans-20 Tablet and Ibuprofen can increase the risk of liver damage.

How to manage the interaction:
Co-administration of Lefuhans-20 Tablet and Ibuprofen can lead to an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, loss of appetite, fatigue, nausea, vomiting, dark-colored urine, light-colored stools, and yellowing of the skin or eyes, consult the doctor immediately. Do not stop using any medications without a doctor's advice.
How does the drug interact with Lefuhans-20 Tablet:
Coadministration of Lefuhans-20 Tablet with clotrimazole can increase the risk of liver problems.

How to manage the interaction:
Although taking Clotrimazole with Lefuhans-20 Tablet may possibly result in an interaction, they can be taken together if prescribed by your doctor. However, if you experience fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, loss of appetite, fatigue, nausea, vomiting, abdominal pain, dark coloured urine, light coloured stools, and/or yellowing of the skin or eyes, consult your doctor immediately. Do not discontinue any medication without consulting your doctor.
How does the drug interact with Lefuhans-20 Tablet:
The combined use of Lefuhans-20 Tablet and Hydrocortisone can increase the risk of infections.

How to manage the interaction:
Co-administration of Lefuhans-20 Tablet and hydrocortisone can lead to an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, blood in phlegm, weight loss, red or inflamed skin, body sores, and pain or burning during urination, consult the doctor immediately. Do not stop using any medications without a doctor's advice.
How does the drug interact with Lefuhans-20 Tablet:
Taking Dexamethasone with Lefuhans-20 Tablet may increase the risk of serious infections.

How to manage the interaction:
Although there is a possible interaction, Dexamethasone can be taken with Lefuhans-20 Tablet if prescribed by the doctor. Consult the doctor immediately if you develop signs and symptoms of infection such as fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, blood in phlegm, weight loss, red or inflamed skin, body sores, and pain or burning during urination. Do not discontinue the medication without consulting a doctor.
How does the drug interact with Lefuhans-20 Tablet:
Coadministration of Ketoconazole and Lefuhans-20 Tablet may cause liver injury.

How to manage the interaction:
Although taking Ketoconazole and Lefuhans-20 Tablet together can result in an interaction, it can be taken if a doctor has prescribed it. However, if you have any of the following symptoms: fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, fatigue, lack of appetite, nausea, vomiting, abdominal pain, dark urine, light stools, and/or yellowing of the skin or eyes, consult a doctor immediately. Do not discontinue any medication without consulting a doctor.
How does the drug interact with Lefuhans-20 Tablet:
Taking Lefuhans-20 Tablet together with tacrolimus may increase the risk of serious infections.

How to manage the interaction:
Although taking tacrolimus and Lefuhans-20 Tablet together can result in an interaction, it can be taken if your doctor has prescribed it. However, consult the doctor immediately if you experience symptoms such as fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, blood in phlegm, red or inflamed skin, body sores, and pain or burning during urination. Do not stop using any medications without consulting a doctor.
How does the drug interact with Lefuhans-20 Tablet:
Taking carbamazepine and Lefuhans-20 Tablet may increase the risk of liver problems.

How to manage the interaction:
Although taking carbamazepine and Lefuhans-20 Tablet together can possibly result in an interaction, it can be taken if your doctor has prescribed it. However, if you experience fever, chills, joint pain or swelling, unusual bleeding or wounds, skin rash, itching, tiredness, nausea, vomiting, abdominal pain, dark urine, light stools, yellowing of the skin or eyes, consult your doctor. Do not stop using any medication without consulting your doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Drug-Diseases Interactions

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No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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Drug-Drug Interactions Checker List

  • IBUPROFEN
  • NAPROXEN
  • ACETAMINOPHEN
  • ASPIRIN
  • DULOXETINE
  • PREDNISONE
  • CELECOXIB
  • AZATHIOPRINE
  • MELOXICAM
  • METHOTREXATE
  • ETANERCEPT
  • ADALIMUMAB
  • ABATACEPT
  • INFLIXIMAB
  • HYDROXYCHLOROQUINE

Habit Forming

No

Special Advise

Regular blood tests to monitor your liver function after starting Lefuhans-20 Tablet , and for every 6-8 weeks are advised.

Diet & Lifestyle Advise

  • Physical activity helps in strengthening muscles and relieves joint stiffness. Gentle activities like 20-30minutes of walking or swimming would be helpful.
  • Performing yoga may also help in improving joint flexibility and pain management.
  • Maintain a healthy weight by performing regular low-strain exercises and eating healthy food.
  • Get adequate sleep as resting the muscles can help in reducing inflammation and swelling.
  • De-stress yourself by meditating, reading books, taking a warm bubble bath or listening to soothing music.
  • Acupuncture, massage and physical therapy may also be helpful.
  • Eat food rich in antioxidants such as berries, spinach, kidney beans, dark chocolate, etc.
  • Foods containing flavonoids help in reducing inflammation. These include soy, berries, broccoli, grapes and green tea.
  • Avoid smoking and alcohol consumption.

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